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Effects of fucoidan on chronic renal failure in rats
Zhang, QB; Li, Z; Xu, ZH; Niu, XZ; Zhang, H
2003-06-01
发表期刊PLANTA MEDICA
卷号69期号:6页码:537-541
文章类型Article
摘要The effects of fucoidan on chronic renal failure (CRF) were investigated in vivo in a subtotal nephrectomy CRF model and a cryoinjury induced CRF model in rats. Fucoidan showed renoprotective effects in both models. Fucoidan (100 or 200 mg/kg, orally) significantly decreased elevated serum creatinine and urea nitrogen levels. Histopathological changes of renal. tubules and interstitium were markedly alleviated by fucoidan and the mesangial areas were also greatly reduced. The activities of fucoidan were dose-dependent.
关键词Laminaria Japonica Laminariaceae Fucoidan Chronic Renal Failure Serum Creatinine Serum Urea Nitrogen
收录类别SCI
语种英语
WOS记录号WOS:000184144600011
引用统计
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/33004
专题海洋生物技术研发中心
作者单位1.Acad Sinica, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, QB,Li, Z,Xu, ZH,et al. Effects of fucoidan on chronic renal failure in rats[J]. PLANTA MEDICA,2003,69(6):537-541.
APA Zhang, QB,Li, Z,Xu, ZH,Niu, XZ,&Zhang, H.(2003).Effects of fucoidan on chronic renal failure in rats.PLANTA MEDICA,69(6),537-541.
MLA Zhang, QB,et al."Effects of fucoidan on chronic renal failure in rats".PLANTA MEDICA 69.6(2003):537-541.
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