Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China

doi:10.1016/j.envpol.2020.115245

	Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China
	Peng, Quancai1,2,3,4 ; Song, Jinming1,2,3,4 ; Li, Xuegang 1,2,3,4; Yuan, Huamao 1,2,3,4; Liu, Mengtan 4,6; Duan, Liqin 1,2,3,4; Zuo, Jiulong 5
	2020-11-01
发表期刊	ENVIRONMENTAL POLLUTION
ISSN	0269-7491
卷号	266 页码:13
通讯作者	Song, Jinming(jmsong@qdio.ac.cn)
摘要	Pharmaceutically active compounds (PhACs) have attracted increasing attention due to their large consumption volumes, high bioactivity and potential ecotoxicity. In this study, a total of 150 commonly used drugs were investigated in sediments of Jiaozhou Bay (JZB). Twenty-five target compounds were detected, of which ten were discovered for the first time in marine sediments. The range of total PhAC content was 3.62-21.4 ng/g dry weight. Ketoprofen (2.49 ng/g), oxytetracycline (1.00 ng/g) and roxithromycin (0.97 ng/g) were the preponderant PhACs. PhACs gradually decreased from east to west, and the distribution of PhACs in the sediment was controlled by the source channel, seawater dynamic process and sediment composition. The diatom, organic matter, and clay proportions in the sediments and the nutrients in the overlying water were the most important environmental factors affecting the distribution of PhACs. PhAC pollution in the sediments of the JZB exhibited an increasing trend. Coprostanol could be used as a chemical indicator of the PhAC concentration in JZB sediments. PhACs were mainly derived from direct pollution due to human fecal excretion in the eastern region. Ofloxacin, tetracycline and oxytetracycline were found to pose high or medium risks to aquatic organisms. It is necessary and urgent to improve the treatment technology of drug residues in sewage treatment plants to decrease the pollution of PhAC residues. With the continuous aging of the global population, the use of PhACs will increase rapidly, which may cause more unpredictable threats to the marine ecosystem. Therefore, the monitoring of PhACs in the marine environment needs to be strengthened, and studies on PhAC occurrence and effects must be considered a priority in global environmental research. (C) 2020 Elsevier Ltd. All rights reserved.
关键词	Pharmaceutically active compounds Occurrence Risk assessment Sediments Jiaozhou bay (JZB)
DOI	10.1016/j.envpol.2020.115245
收录类别	SCI
语种	英语
资助项目	Fund of the Key Science and Technology Innovation Program - Shandong Province ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0504-1] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA23050501] ; National Natural Science Foundation of China[41676068] ; Development of Instrument & Equipment Function and Technical Innovation Project of CAS[HYQYGNKF2016-1-2]
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:000571443200007
出版者	ELSEVIER SCI LTD
引用统计	被引频次：12[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/168832
专题	海洋生态与环境科学重点实验室胶州湾海洋生态系统国家野外研究站
通讯作者	Song, Jinming
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 5.Hebei Agr Univ, Ocean Coll, Qinhuangdao 066000, Hebei, Peoples R China 6.Chinese Acad Sci, Inst Oceanol, Jiaozhou Bay Natl Marine Ecosyst Res Stn, Qingdao 266071, Peoples R China
第一作者单位	海洋生态与环境科学重点实验室; 中国科学院海洋大科学研究中心
通讯作者单位	海洋生态与环境科学重点实验室; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Peng, Quancai,Song, Jinming,Li, Xuegang,et al. Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China[J]. ENVIRONMENTAL POLLUTION,2020,266:13.
APA	Peng, Quancai.,Song, Jinming.,Li, Xuegang.,Yuan, Huamao.,Liu, Mengtan.,...&Zuo, Jiulong.(2020).Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China.ENVIRONMENTAL POLLUTION,266,13.
MLA	Peng, Quancai,et al."Pharmaceutically active compounds (PhACs) in surface sediments of the Jiaozhou Bay, north China".ENVIRONMENTAL POLLUTION 266(2020):13.

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