Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Halogenated Compounds from Corals: Chemical Diversity and Biological Activities | |
| Zhang, Yuanyuan1; Liu, Junhong1; Shi, Dayong2,3; Li, Zheng1 | |
| 2019 | |
| Source Publication | MINI-REVIEWS IN MEDICINAL CHEMISTRY
 |
| ISSN | 1389-5575 |
| Volume | 19Issue:15Pages:1204-1218 |
| Corresponding Author | Liu, Junhong(liujh@qust.edu.cn) ; Shi, Dayong(shidayong@qdio.ac.cn) |
| Abstract | As important marine biological resources, corals produce a large amount of active organic compounds in their secondary metabolic processes, including numerous brominated, chlorinated, and iodinated compounds. These compounds, with novel structures and unique activities, guide the discovery and research of important lead compounds and novel biological mechanisms. Through a large number of literature surveys, this paper summarized a total of 145 halogenated secondary metabolites which were roughly divided into four major classes of terpenes, prostaglandins, steroids and alkaloids, and they were mainly isolated from ten coral families, Ellisellidae, Gorgoniidae, Briareidae, Plexauridae, Anthothelidae, Alcyoniidae, Clavularidae, Tubiporidae, Nephtheidae and Dendrophyllidae to the best of our knowledge. In addition, their organism species, structure composition and biological activity were also discussed in the form of a chart in this essay. |
| Keyword | Marine corals metabolites halogenated bioactivity chemical diversity |
| DOI | 10.2174/1389557518666181113124015 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[81773586] ; National Natural Science Foundation of China[81703354] ; Key research and development project of Shandong province[2016GSF201193] ; Key research and development project of Shandong province[2016ZDJS07A13] ; Key research and development project of Shandong province[2016GSF115002] ; Key research and development project of Shandong province[2016GSF115009] ; CAS[QYZDB-SSW-DQC014] ; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences[ZSTH026] ; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; National Program for Support of Top-notch Young Professionals ; Taishan scholar Youth Project of Shandong province |
| WOS Research Area | Pharmacology & Pharmacy |
| WOS Subject | Chemistry, Medicinal |
| WOS ID | WOS:000493818600002 |
| Publisher | BENTHAM SCIENCE PUBL LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/164827 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Liu, Junhong; Shi, Dayong |
| Affiliation | 1.Qingdao Univ Sci & Technol, Dept Pharmaceut, Qingdao 266042, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,et al. Halogenated Compounds from Corals: Chemical Diversity and Biological Activities[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2019,19(15):1204-1218. |
| APA | Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,&Li, Zheng.(2019).Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.MINI-REVIEWS IN MEDICINAL CHEMISTRY,19(15),1204-1218. |
| MLA | Zhang, Yuanyuan,et al."Halogenated Compounds from Corals: Chemical Diversity and Biological Activities".MINI-REVIEWS IN MEDICINAL CHEMISTRY 19.15(2019):1204-1218. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment