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Halogenated Compounds from Corals: Chemical Diversity and Biological Activities
Zhang, Yuanyuan1; Liu, Junhong1; Shi, Dayong2,3; Li, Zheng1
2019
Source PublicationMINI-REVIEWS IN MEDICINAL CHEMISTRY
ISSN1389-5575
Volume19Issue:15Pages:1204-1218
Corresponding AuthorLiu, Junhong(liujh@qust.edu.cn) ; Shi, Dayong(shidayong@qdio.ac.cn)
AbstractAs important marine biological resources, corals produce a large amount of active organic compounds in their secondary metabolic processes, including numerous brominated, chlorinated, and iodinated compounds. These compounds, with novel structures and unique activities, guide the discovery and research of important lead compounds and novel biological mechanisms. Through a large number of literature surveys, this paper summarized a total of 145 halogenated secondary metabolites which were roughly divided into four major classes of terpenes, prostaglandins, steroids and alkaloids, and they were mainly isolated from ten coral families, Ellisellidae, Gorgoniidae, Briareidae, Plexauridae, Anthothelidae, Alcyoniidae, Clavularidae, Tubiporidae, Nephtheidae and Dendrophyllidae to the best of our knowledge. In addition, their organism species, structure composition and biological activity were also discussed in the form of a chart in this essay.
KeywordMarine corals metabolites halogenated bioactivity chemical diversity
DOI10.2174/1389557518666181113124015
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[81773586] ; National Natural Science Foundation of China[81703354] ; Key research and development project of Shandong province[2016GSF201193] ; Key research and development project of Shandong province[2016ZDJS07A13] ; Key research and development project of Shandong province[2016GSF115002] ; Key research and development project of Shandong province[2016GSF115009] ; CAS[QYZDB-SSW-DQC014] ; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences[ZSTH026] ; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; National Program for Support of Top-notch Young Professionals ; Taishan scholar Youth Project of Shandong province
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal
WOS IDWOS:000493818600002
PublisherBENTHAM SCIENCE PUBL LTD
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/164827
Collection实验海洋生物学重点实验室
Corresponding AuthorLiu, Junhong; Shi, Dayong
Affiliation1.Qingdao Univ Sci & Technol, Dept Pharmaceut, Qingdao 266042, Shandong, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,et al. Halogenated Compounds from Corals: Chemical Diversity and Biological Activities[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2019,19(15):1204-1218.
APA Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,&Li, Zheng.(2019).Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.MINI-REVIEWS IN MEDICINAL CHEMISTRY,19(15),1204-1218.
MLA Zhang, Yuanyuan,et al."Halogenated Compounds from Corals: Chemical Diversity and Biological Activities".MINI-REVIEWS IN MEDICINAL CHEMISTRY 19.15(2019):1204-1218.
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