Involvement of clustered oyster Wnt genes in gut formation

doi:10.1007/s00343-018-7138-1

IOCAS-IR > 实验海洋生物学重点实验室

	Involvement of clustered oyster Wnt genes in gut formation
	Liu Jun 1,2,4; Xu Fei 1,3,4; Ji Peng1,2,4 ; Li Li 1,4,5; Zhang Guofan 1,3,4
	2018-09-01
发表期刊	JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN	2096-5508
卷号	36 期号:5 页码:1746-1752
通讯作者	Xu Fei(xufei@qdio.ac.cn) ; Zhang Guofan(gfzhang@qdio.ac.cn)
摘要	Genes encoding Wnt ligands play important roles in organ development. The Wnt10-Wnt6-Wnt1-Wnt9 cluster widely presents in many metazoan genomes, indicating the importance of gene arrangement. Hypothesis has been proposed that they may be coordinately regulated. However, few expression correlations were identified in model animals. We analyzed the tissue expression pattern of clustered oyster Wnt10, Wnt6, Wnt1, and Wnt9a genes in this study. The results indicated the highest expression level in adult gut system of these clustered Wnt genes, except for Wnt6, which had highest expression in mantle. Further whole-mount immunofluorescence assay indicated that Wnt6 protein was restricted to gut region in oyster larvae. These results suggest the possible important role of the Wnt10-Wnt6-Wnt1-Wnt9 cluster in oyster gut formation.
关键词	gene cluster tissue distribution digestive gland immunofluorescence Crassostrea gigas
DOI	10.1007/s00343-018-7138-1
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[31402285] ; National Natural Science Foundation of China[31530079] ; Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; earmarked fund for Modern Agro-industry Technology Research System[CARS-49] ; Scientific and Technological Innovation Project ; National Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[31402285] ; National Natural Science Foundation of China[31530079] ; Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; earmarked fund for Modern Agro-industry Technology Research System[CARS-49] ; Scientific and Technological Innovation Project
WOS研究方向	Marine & Freshwater Biology ; Oceanography
WOS类目	Limnology ; Oceanography
WOS记录号	WOS:000450165300025
出版者	SCIENCE PRESS
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/156412
专题	实验海洋生物学重点实验室
通讯作者	Xu Fei; Zhang Guofan
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266000, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 5.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266000, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Liu Jun,Xu Fei,Ji Peng,et al. Involvement of clustered oyster Wnt genes in gut formation[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2018,36(5):1746-1752.
APA	Liu Jun,Xu Fei,Ji Peng,Li Li,&Zhang Guofan.(2018).Involvement of clustered oyster Wnt genes in gut formation.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,36(5),1746-1752.
MLA	Liu Jun,et al."Involvement of clustered oyster Wnt genes in gut formation".JOURNAL OF OCEANOLOGY AND LIMNOLOGY 36.5(2018):1746-1752.

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