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Inhibitory effects of Enteromorpha linza polysaccharide on micronucleus of Allium sativum root cells
Zhang, Zhongshan1; Wang, Xiaomei1; Li, Jingfen1; Liu, Chongbin1; Zhang, Quanbin2
2016-06-01
发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷号87页码:252-255
文章类型Article
摘要In this study, the antimutagenic function of the polysaccharide from Enteromorpha linza with the micronucleus test of Allium sativum root cells induced by sulfur dioxide and ultraviolet was studied. The concentration-effect relation of the two inducers was firstly evaluated. The results showed that an increase of genotoxicity damage was demonstrated and micronuclei frequency induced by sulfur dioxide and ultraviolet displayed dose dependent increases. All the doses of polysaccharide did affect the micronuclei frequency formation compared with the negative control. And also, the significant increase in inhibition rate of micronuclei frequency was observed with the increase of the dose of polysaccharide. It was showed maximum inhibition of micronuclei frequency cells (71.74% and 66.70%) at a concentration of 200 g/mL in three experiments. The low molecular weight polysaccharide showed higher inhibition rate than raw polysaccharide at the higher concentration (50 g/mL) in the absence of sulfur dioxide and ultraviolet. It was confirmed to be a good mutant inhibitor. (C) 2016 Elsevier B.V. All rights reserved.
关键词Enteromorpha Linza Polysaccharide Antimutation
DOI10.1016/j.ijbiomac.2016.02.065
收录类别SCI
语种英语
WOS记录号WOS:000374811300031
引用统计
文献类型期刊论文
版本出版稿
条目标识符http://ir.qdio.ac.cn/handle/337002/131030
专题海洋生物技术研发中心
作者单位1.Huzhou Univ, Dept Med, Huzhou 313000, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Zhongshan,Wang, Xiaomei,Li, Jingfen,et al. Inhibitory effects of Enteromorpha linza polysaccharide on micronucleus of Allium sativum root cells[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,87:252-255.
APA Zhang, Zhongshan,Wang, Xiaomei,Li, Jingfen,Liu, Chongbin,&Zhang, Quanbin.(2016).Inhibitory effects of Enteromorpha linza polysaccharide on micronucleus of Allium sativum root cells.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,87,252-255.
MLA Zhang, Zhongshan,et al."Inhibitory effects of Enteromorpha linza polysaccharide on micronucleus of Allium sativum root cells".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 87(2016):252-255.
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