Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila

doi:10.3390/molecules16042796

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	Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila
	Wang, Cui-Cui 1,2; Liu, Hai-Zhou 1; Liu, Ming 1; Zhang, Yu-Yan 1; Li, Tian-Tian 1,2; Lin, Xiu-Kun 1
	2011-04-01
发表期刊	MOLECULES
ISSN	1420-3049
卷号	16 期号:4 页码:2796-2801
文章类型	Article
摘要	A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.; A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
关键词	Polyketide Chromone Indole Alkaloid Mosher Exophiala Pisciphila
学科领域	Chemistry
DOI	10.3390/molecules16042796
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000289236200005
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/11827
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,et al. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila[J]. MOLECULES,2011,16(4):2796-2801.
APA	Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,Zhang, Yu-Yan,Li, Tian-Tian,&Lin, Xiu-Kun.(2011).Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila.MOLECULES,16(4),2796-2801.
MLA	Wang, Cui-Cui,et al."Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila".MOLECULES 16.4(2011):2796-2801.

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