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Divergence and plasticity shape adaptive potential of the Pacific oyster 期刊论文
NATURE ECOLOGY & EVOLUTION, 2018, 卷号: 2, 期号: 11, 页码: 1751-1760
Authors:  Li, Li;  Li, Ao;  Song, Kai;  Meng, Jie;  Guo, Ximing;  Li, Shiming;  Li, Chunyan;  De Wit, Pierre;  Que, Huayong;  Wu, Fucun;  Wang, Wei;  Qi, Haigang;  Xu, Fei;  Cong, Rihao;  Huang, Baoyu;  Li, Yingxiang;  Wang, Ting;  Tang, Xueying;  Liu, Sheng;  Li, Busu;  Shi, Ruihui;  Liu, Youli;  Bu, Chen;  Zhang, Chi;  He, Weiming;  Zhao, Shancen;  Li, Hongjun;  Zhang, Shoudu;  Zhang, Linlin;  Zhang, Guofan
Favorite  |  View/Download:18/0  |  Submit date:2019/05/15
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
Authors:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Favorite  |  View/Download:0/0  |  Submit date:2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
Authors:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling;  Li, Xiangqian;  Wang, Lijun;  Guo, Chuanlong;  Wu, Ning;  Shi, Dayong
Favorite  |  View/Download:0/0  |  Submit date:2019/08/20
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
Authors:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Favorite  |  View/Download:7/0  |  Submit date:2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
Authors:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  Favorite  |  View/Download:55/0  |  Submit date:2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
Authors:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  Favorite  |  View/Download:54/0  |  Submit date:2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
Authors:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
Adobe PDF(1892Kb)  |  Favorite  |  View/Download:45/0  |  Submit date:2017/09/30
Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
Quantitative assessment of free gas beneath gas hydrate stability zone from prestack seismic data and rock physics: a case of hole NGHP01-10A, Krishna-Godavari basin, India 期刊论文
CHINESE JOURNAL OF GEOPHYSICS-CHINESE EDITION, 2016, 卷号: 59, 期号: 7, 页码: 2553-2563
Authors:  Qian Jin;  Wang Xiu-Juan;  Dong Dong-Dong;  Wu Shi-Guo;  Kalachand, Sain;  Ye Yue-Ming
Adobe PDF(6150Kb)  |  Favorite  |  View/Download:35/0  |  Submit date:2016/09/19
Gas Hydrate  Rock Physics  Avo  Quantitative Assessment  Free Gas Saturation  
3D P wave velocity structures of crust and their relationship with earthquakes in the Shandong area 期刊论文
CHINESE JOURNAL OF GEOPHYSICS-CHINESE EDITION, 2016, 卷号: 59, 期号: 4, 页码: 1335-1349
Authors:  Su Dao-Lei;  Fan Jian-Ke;  Wu Shi-Guo;  Chen Chuan-Xu;  Dong Xiao-Na;  Chen Shi-Jun
Adobe PDF(6387Kb)  |  Favorite  |  View/Download:78/0  |  Submit date:2016/08/25
Shandong Area  Seismic Tomography  3d Crustal Structure  Seismicity  
Tomographic evidence for a slab tear induced by fossil ridge subduction at Manila Trench, South China Sea 期刊论文
INTERNATIONAL GEOLOGY REVIEW, 2015, 卷号: 57, 期号: 5-8, 页码: 998-1013
Authors:  Fan, Jian-ke;  Wu, Shi-guo;  Spence, George
Adobe PDF(3053Kb)  |  Favorite  |  View/Download:104/0  |  Submit date:2015/06/15
Tomography  Ridge Subduction  Manila Trench  Slab Tear  South China Sea