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中国科学院海洋研究所机构知识库
Knowledge Management System Of Institute of Oceanology, Chinese Academy of Sciences
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Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 9, 页码: 10089-10103
Authors:
Liu, Ge
;
Kuang, Shan
;
Cao, Ruobing
;
Wang, Ju
;
Peng, Quancai
;
Sun, Chaomin
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View/Download:2/0
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Submit date:2019/11/14
stearoyl CoA desaturase 1
monounsaturated FAs
ATP production
海洋细菌胞外多糖EPS11抗肿瘤转移机制研究
学位论文
理学硕士, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:
王菊
Adobe PDF(2792Kb)
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Submit date:2019/06/17
海洋细菌
多糖eps11
癌症
黏附
转移
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth and Metastasis via Blocking Cell Adhesion and Attenuating Filiform Structure Formation
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 15
Authors:
Wang, Ju
;
Liu, Ge
;
Ma, Weiping
;
Lu, Zhongxia
;
Sun, Chaomin
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View/Download:4/0
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Submit date:2019/08/28
polysaccharide
EPS11
cancer
filiform structure
adhesion
CD99
metastasis
Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 8, 页码: 1745-1751
Authors:
Xiao, Fei
;
Li, Huayue
;
Xu, Mingyuan
;
Li, Tong
;
Wang, Ju
;
Sun, Chaomin
;
Hong, Kui
;
Li, Wenli
Adobe PDF(974Kb)
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Submit date:2019/08/23
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
Authors:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Guo, Shu-Ju
;
Li, Xiang-Qian
;
Chen, Xue-Chun
;
Luo, Jiao
;
Li, Chao
;
Wang, Yi
;
Shi, Da-Yong
Adobe PDF(824Kb)
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Submit date:2019/08/21
Pyrimidinedionederivatives
DPP-4 inhibitor
Molecular hybrid
SARs
Type 2 diabetes
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
Authors:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Li, Xiang-qian
;
Guo, Chuan-long
;
Guo, Shu-ju
;
Shi, Da-Yong
Adobe PDF(1523Kb)
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Submit date:2019/08/21
DPP-4
Inhibitors
Analogs
Physico-chemical properties
SARs
Type 2 diabetes
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 3, 页码: 18
Authors:
Cao, Ruobing
;
Jin, Weihua
;
Shan, Yeqi
;
Wang, Ju
;
Liu, Ge
;
Kuang, Shan
;
Sun, Chaomin
Adobe PDF(10029Kb)
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View/Download:4/0
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Submit date:2019/08/21
polysaccharide
cancer
filiform structures
beta III-tubulin
anoikis
adhesion
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
Authors:
Guo, Chuan-Long
;
Wang, Li-Jun
;
Zhao, Yue
;
Liu, Hua
;
Li, Xiang-Qian
;
Jiang, Bo
;
Luo, Jiao
;
Guo, Shu-Ju
;
Wu, Ning
;
Shi, Da-Yong
Adobe PDF(5208Kb)
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Submit date:2019/08/21
bromophenol
molecular mechanisms
apoptosis
cell cycle
PI3K
Akt
p38
ERK
ROS
human lung cancer
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation
期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
Authors:
Wang, Li-Jun
;
Guo, Chuan-Long
;
Li, Xiang-Qian
;
Wang, Shuai-Yu
;
Jiang, Bo
;
Zhao, Yue
;
Luo, Jiao
;
Xu, Kuo
;
Liu, Hua
;
Guo, Shu-Ju
;
Wu, Ning
;
Shi, Da-Yong
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Submit date:2019/07/15
bromophenol hybrids
anticancer
structure-activity relationships
ROS
apoptotic pathway
Facile fabrication of AgI/BiVO4 composites with enhanced visible photocatalytic degradation and antibacterial ability
期刊论文
JOURNAL OF ALLOYS AND COMPOUNDS, 2017, 卷号: 721, 页码: 622-627
Authors:
Xiang, Zhenbo
;
Wang, Yi
;
Ju, Peng
;
Long, Yang
;
Zhang, Dun
Adobe PDF(2367Kb)
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View/Download:66/0
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Submit date:2017/09/29
Agi
Bivo4
Photocatalysis
Degradation
Antibacterial
Visible Light