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Loading Effect of Chitosan Derivative Nanoparticles on Different Antigens and Their Immunomodulatory Activity on Dendritic Cells 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 10, 页码: 15
作者:  Xu, Chaojie;  Xing, Ronge;  Liu, Song;  Qin, Yukun;  Li, Kecheng;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2195Kb)  |  收藏  |  浏览/下载:171/0  |  提交时间:2022/01/05
chitosan derivative nanoparticles  different antigens  antigen selectivity  encapsulation efficiency  immune effects  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:287/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
CoMoO4 nanobelts as efficient peroxidase mimics for the colorimetric determination of H2O2 期刊论文
MICROCHIMICA ACTA, 2020, 卷号: 187, 期号: 8, 页码: 14
作者:  Wang, Zhe;  Ju, Peng;  Zhang, Yu;  Jiang, Fenghua;  Ding, Haibing;  Sun, Chengjun
Adobe PDF(8815Kb)  |  收藏  |  浏览/下载:214/0  |  提交时间:2020/09/25
Peroxidase mimics  Catalytic mechanism  Rapid detection  Selectivity  Kinetics  Nanobelts  XRD  SEM  TMB  H2O2  
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Adobe PDF(2321Kb)  |  收藏  |  浏览/下载:187/0  |  提交时间:2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载:308/0  |  提交时间:2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载:252/0  |  提交时间:2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
The design strategy of selective PTP1B inhibitors over TCPTP 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 16, 页码: 3343-3352
作者:  Li, XiangQian;  Wang, LiJun;  Shi, DaYong
Adobe PDF(2312Kb)  |  收藏  |  浏览/下载:192/1  |  提交时间:2016/12/05
Selectivity  Ptp1b Inhibitor  Tcptp  Diabetes  Design Strategy