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Identification of Streptomyces sp nov WH26 producing cytotoxic compounds isolated from marine solar saltern in China 期刊论文
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2013, 卷号: 29, 期号: 7, 页码: 1271-1278
Authors:  Liu, Haizhou;  Xiao, Lin;  Wei, Jianteng;  Schmitz, John C.;  Liu, Ming;  Wang, Cuicui;  Cheng, Linyou;  Wu, Ning;  Chen, Lei;  Zhang, Yuyan;  Lin, Xiukun;  Lin, XK
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Moderately Halophilic Actinomycetes  Streptomyces  8-o-methyltetrangulol  Naphthomycin a  
Mere15, a novel polypeptide from Meretrix meretrix, inhibits adhesion, migration and invasion of human lung cancer A549 cells via down-regulating MMPs 期刊论文
PHARMACEUTICAL BIOLOGY, 2013, 卷号: 51, 期号: 2, 页码: 145-151
Authors:  Wang, Hui;  Wei, Jianteng;  Wu, Ning;  Liu, Ming;  Wang, Cuicui;  Zhang, Yuyan;  Wang, Fengxia;  Liu, Haizhou;  Lin, Xiukun;  Lin, XK
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Anticancer  Cancer Metastasis  Transwell Assay  Gelatin Zymography  Rt-pcr  
Induction of Apoptosis, G(0)/G(1) Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus 期刊论文
MARINE DRUGS, 2012, 卷号: 10, 期号: 11, 页码: 2596-2607
Authors:  Liu, Ming;  Zhao, Xiangzhong;  Zhao, Jin;  Xiao, Lin;  Liu, Haizhou;  Wang, Cuicui;  Cheng, Linyou;  Wu, Ning;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
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Meretrix Meretrix Linnaeus  Mere15  Apoptosis  Anticancer  
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文
EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450
Authors:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning;  Zheng, Lanhong;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
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Meretrix Meretrix Linnaeus  Antitumor Polypeptide  Non-small-cell Lung Carcinoma  g(2)/m Phase Arrest  Apoptosis  
真菌PHF-9化学成分及其抗肿瘤活性研究 期刊论文
中国新药杂志, 2012, 期号: 14, 页码: 1660-1664
Authors:  王翠翠;  刘明;  魏鉴腾;  王惠;  林秀坤
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Exopisiod 1  吲哚生物碱  抗肿瘤活性  凋亡  
文蛤多肽抑制肿瘤细胞微管蛋白聚合 期刊论文
中国生化药物杂志, 2012, 期号: 3, 页码: 225-228
Authors:  王翠翠;  刘明;  王凤霞;  林秀坤
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抗肿瘤多肽  A549细胞  细胞周期阻滞  微管蛋白聚合  
一种苯酚类化合物及其制备方法和应用 专利
专利类型: 发明, 专利号: CN201110080563.2, 申请日期: 2011-09-28, 公开日期: 2011-09-28
Inventors:  林秀坤;  王翠翠;  刘明;  刘海洲;  张玉艳;  宋彦卓
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一种苯酚类化合物  其特征在于:苯酚类化合物如图(i)所示fsa00000464049500011.tif  
一种玻璃海鞘多肽及其制备 专利
专利类型: 发明, 专利号: CN201010620668.8, 申请日期: 2011-09-07, 公开日期: 2011-09-07
Inventors:  林秀坤;  程林友;  魏建腾;  郑兰红;  王翠翠
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一种玻璃海鞘多肽  其特征在于:玻璃海鞘多肽n?末端序列为yqpdkfmlrgelrnn  分子量为5931da  等电点为7.25。  
一种文蛤多肽及其制备方法 专利
专利类型: 发明, 专利号: CN201110036545.4, 申请日期: 2011-08-24, 公开日期: 2011-08-24
Inventors:  林秀坤;  王翠翠;  王惠;  程林友;  郑兰红;  刘明
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一种文蛤多肽  其特征在于:所述文蛤多肽n?末端序列为ideiqntgggtnfr  其分子量为15kda  等电点为8.85。  
一种文蛤多肽的应用 专利
专利类型: 发明, 专利号: CN201110036543.5, 申请日期: 2011-07-20, 公开日期: 2011-07-20
Inventors:  林秀坤;  王翠翠;  刘明;  魏鉴腾
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一种文蛤多肽的应用  其特征在于:文蛤多肽在制备预防和/或治疗恶性肿瘤药物中的应用。