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Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Favorite  |  View/Download:10/0  |  Submit date:2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
海洋天然产物BDDPM靶向调控PTP1B的降糖作用及机制研究 学位论文
, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:  李超
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Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
Authors:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
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type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
Authors:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
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Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
CYC27 Synthetic Derivative of Bromophenol from Red Alga Rhodomela confervoides: Anti-Diabetic Effects of Sensitizing Insulin Signaling Pathways and Modulating RNA Splicing-Associated RBPs 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 15
Authors:  Luo, Jiao;  Jiang, Bo;  Li, Chao;  Jia, Xiaoling;  Shi, Dayong
Favorite  |  View/Download:3/0  |  Submit date:2019/08/28
brominated organic compounds  hypoglycemic activity  insulin-sensitizing effect  RBPs  RNA splicing  
Carbon pools and fluxes in the China Seas and adjacent oceans 期刊论文
SCIENCE CHINA-EARTH SCIENCES, 2018, 卷号: 61, 期号: 11, 页码: 1535-1563
Authors:  Jiao, Nianzhi;  Liang, Yantao;  Zhang, Yongyu;  Liu, Jihua;  Zhang, Yao;  Zhang, Rui;  Zhao, Meixun;  Dai, Minhan;  Zhai, Weidong;  Gao, Kunshan;  Song, Jinming;  Yuan, Dongliang;  Li, Chao;  Lin, Guanghui;  Huang, Xiaoping;  Yan, Hongqiang;  Hu, Limin;  Zhang, Zenghu;  Wang, Long;  Cao, Chunjie;  Luo, Yawei;  Luo, Tingwei;  Wang, Nannan;  Dang, Hongyue;  Wang, Dongxiao;  Zhang, Si
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China Seas  "Source" or "sink" of CO2  Carbon pool  Carbon flux  Biological pump  Microbial carbon pump  
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
Authors:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
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Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Draft genome of the Peruvian scallop Argopecten purpuratus 期刊论文
GIGASCIENCE, 2018, 卷号: 7, 期号: 4, 页码: 6
Authors:  Li, Chao;  Liu, Xiao;  Liu, Bo;  Ma, Bin;  Liu, Fengqiao;  Liu, Guilong;  Shi, Qiong;  Wang, Chunde
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Argopecten purpuratus  Peruvian scallop  genome assembly  annotation  gene prediction  phylogenetic analysis  
Interactions of the Greater Ontong Java mantle plume component with the Osbourn Trough 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:  Zhang, Guo-Liang;  Li, Chao
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海参加工工艺评价及其加工废弃液活性物质研究 学位论文
: 中国科学院研究生院, 2013
Authors:  李超峰
Adobe PDF(3661Kb)  |  Favorite  |  View/Download:73/1  |  Submit date:2014/08/08
刺参  加工工艺  加工废弃液  生物活性