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Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：301/0  |  提交时间：2020/03/20
Salinity variability in the tropical Pacific during the Central-Pacific and Eastern-Pacific El Nino events 期刊论文
JOURNAL OF MARINE SYSTEMS, 2019, 卷号: 199, 页码: 14
作者:  Qi, Jifeng;  Zhang, Linlin;  Qu, Tangdong;  Yin, Baoshu;  Xu, Zhenhua;  Yang, Dezhou;  Li, Delei;  Qin, Yinghao
Adobe PDF(6846Kb)  |  收藏  |  浏览/下载：291/0  |  提交时间：2020/01/03
Sea surface salinity  El Nino  Tropical Pacific  ORAS4 reanalysis  
Spatial pattern of benthic macroinvertebrate communities and their relationship with environmental variables on the East China Sea shelf 期刊论文
DEEP-SEA RESEARCH PART II-TOPICAL STUDIES IN OCEANOGRAPHY, 2019, 卷号: 169, 页码: 11
作者:  Xu, Yong;  Sui, Jixing;  Ma, Lin;  Dong, Dong;  Kou, Qi;  Gan, Zhibin;  Gong, Lin;  Yang, Mei;  Li, Xinzheng;  Wang, Jinbao;  Wang, Hongfa
Adobe PDF(2729Kb)  |  收藏  |  浏览/下载：282/0  |  提交时间：2020/03/20
Macrofauna  Community structure  Diversity  Spatial variation  East China sea  
Deciphering the Origin and Evolution of the X1X2Y System in Two Closely-Related Oplegnathus Species (Oplegnathidae and Centrarchiformes) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 14, 页码: 16
作者:  Xu, Dongdong;  Sember, Alexandr;  Zhu, Qihui;  de Oliveira, Ezequiel Aguiar;  Liehr, Thomas;  Al-Rikabi, Ahmed B. H.;  Xiao, Zhizhong;  Song, Hongbin;  Cioffi, Marcelo de Bello
Adobe PDF(2865Kb)  |  收藏  |  浏览/下载：331/0  |  提交时间：2019/11/14
comparative genomic hybridization  centric fusion  multiple sex chromosomes  Oplegnathus  whole chromosome painting  
溴酚化合物靶向PTP1B改善胰岛素抵抗和抗胰腺癌的作用机制研究 学位论文
, 中国科学院海洋研究所: 中国科学院大学, 2019
作者:  徐琦
Adobe PDF(6967Kb)  |  收藏  |  浏览/下载：176/0  |  提交时间：2019/06/17
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
收藏  |  浏览/下载：322/0  |  提交时间：2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Adobe PDF(2321Kb)  |  收藏  |  浏览/下载：195/0  |  提交时间：2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Statistical Bias Correction for Simulated Wind Speeds Over CORDEX-East Asia 期刊论文
EARTH AND SPACE SCIENCE, 2019, 卷号: 6, 期号: 2, 页码: 200-211
作者:  Li, Delei;  Feng, Jianlong;  Xu, Zhenhua;  Yin, Baoshu;  Shi, Hongyuan;  Qi, Jifeng
Adobe PDF(18193Kb)  |  收藏  |  浏览/下载：239/0  |  提交时间：2019/05/15
Ecosystem attributes of trophic models before and after construction of artificial oyster reefs using Ecopath 期刊论文
AQUACULTURE ENVIRONMENT INTERACTIONS, 2019, 卷号: 11, 页码: 111-127
作者:  Xu, Min;  Qi, Lu;  Zhang, Li-bing;  Zhang, Tao;  Yang, Hong-sheng;  Zhang, Yun-ling
Adobe PDF(949Kb)  |  收藏  |  浏览/下载：374/0  |  提交时间：2019/05/15
Ecopath model  Artificial oyster reef  Apostichopus japonicus  Rapana venosa  Ecosystem properties  Sea ranching  
70年来中国化学海洋学研究的主要进展 期刊论文
海洋学报, 2019, 卷号: 41, 期号: 10, 页码: 65
作者:  宋金明;  王启栋;  张润;  陈建芳;  陈敏;  徐忠胜
收藏  |  浏览/下载：255/0  |  提交时间：2020/01/03