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Pontivivens ytuae sp. nov., isolated from deep sea sediment of the Mariana Trench 期刊论文
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2021, 卷号: 71, 期号: 9, 页码: 6
作者:  Wang, Zhen;  Du, Rong-bin;  Sun, Qing-lei;  Sun, Yuan-yuan;  Zhang, Jian;  Tang, Yong-zheng
Adobe PDF(273Kb)  |  收藏  |  浏览/下载:116/0  |  提交时间:2022/02/18
Mariana Trench  Pontivivens  sediment  Rhodobacteraceae  
Antifungal Prenylated Diphenyl Ethers from Arthrinium arundinis, an Endophytic Fungus Isolated from the Leaves of Tobacco (Nicotiana tabacum L.) 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 7
作者:  Zhang, Peng;  Li, Xin;  Yuan, Xiao-Long;  Du, Yong-Mei;  Wang, Bin-Gui;  Zhang, Zhong-Feng
Adobe PDF(820Kb)  |  收藏  |  浏览/下载:261/0  |  提交时间:2019/05/15
tobacco-derived endophytic fungus  Arthrinium arundinis  Nicotiana tabacum L  prenylated diphenyl ethers  antifungal activity  cytotoxicity  
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
Adobe PDF(824Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2019/08/21
Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载:276/0  |  提交时间:2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
A comparative study on oxidative stress response in the hepatopancreas and midgut of the white shrimp Litopenaeus vannamei under gradual changes to low or high pH environment 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 76, 页码: 27-34
作者:  Han, Si-yin;  Wang, Meng-qiang;  Wang, Bao-jie;  Liu, Mei;  Jiang, Ke-yong;  Wang, Lei
Adobe PDF(2362Kb)  |  收藏  |  浏览/下载:295/0  |  提交时间:2019/08/21
Litopenaeus vannamei  Hepatopancreas  Midgut  Gradual-low pH  Gradual-high pH  Antioxidant  
Adaptation of the white shrimp Litopenaeus vannamei to gradual changes to a low-pH environment 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 149, 页码: 203-210
作者:  Han, Si-yin;  Wang, Bao-jie;  Liu, Mei;  Wang, Meng-qiang;  Jiang, Ke-yong;  Liu, Xin-wei;  Wang, Lei
Adobe PDF(933Kb)  |  收藏  |  浏览/下载:256/0  |  提交时间:2019/08/21
Litopenaeus vannamei  Gradual-low pH  Mortality  Growth performance  Osmoregulation  Vibrio parahemolyticus  
Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia 期刊论文
AQUACULTURE, 2018, 卷号: 490, 页码: 44-52
作者:  Han, Si-yin;  Wang, Meng-qiang;  Liu, Mei;  Wang, Bao-jie;  Jiang, Ke-yong;  Wang, Lei
Adobe PDF(621Kb)  |  收藏  |  浏览/下载:229/0  |  提交时间:2019/08/21
Litopenaeus vannamei  Hepatopancreas  Midgut  Cyclic serious/medium hypoxia  Oxidative stress  Gene expression  
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Adobe PDF(5208Kb)  |  收藏  |  浏览/下载:305/0  |  提交时间:2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载:275/0  |  提交时间:2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载:308/0  |  提交时间:2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity