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Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA-cGAS-STING pathway 期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 卷号: 233, 页码: 12
作者:  Dong, Kehong;  Sun, Yuxuan;  Gao, Xintao;  Wang, Jing;  Wu, Xiaochen;  Guo, Chuanlong
收藏  |  浏览/下载：0/0  |  提交时间：2024/04/07
Acetaminophen  Liver injury  Hesperidin  MtDNA  CGAS-STING  
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2023, 卷号: 177, 页码: 10
作者:  Liu, Shuai;  Gao, Xintao;  Yin, Yulan;  Wang, Jing;  Dong, Kehong;  Shi, Dayong;  Wu, Xiaochen;  Guo, Chuanlong
收藏  |  浏览/下载：74/0  |  提交时间：2023/12/13
Silk fibroin peptide  Naringin  Acute kidney injury  Mitophagy  cGAS-STING pathway  
The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 22, 页码: 12
作者:  Qiang, Xi;  Guo, Chuanlong;  Gu, Wenhui;  Song, Yuling;  Zhang, Yuhong;  Gong, Xiangzhong;  Wang, Lijun;  Wang, Guangce
Adobe PDF(6346Kb)  |  收藏  |  浏览/下载：120/0  |  提交时间：2023/01/04
obesity  lipid metabolism  phycobiliproteins  fucoxanthin  krill oil  
EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 352, 页码: 10
作者:  Qi, Xueju;  Zhang, Shuna;  Chen, Zekun;  Wang, Lijun;  Zhu, Wenyong;  Yin, Chuanjin;  Fan, Junting;  Wu, Xiaochen;  Wang, Jing;  Guo, Chuanlong
Adobe PDF(10635Kb)  |  收藏  |  浏览/下载：131/0  |  提交时间：2022/07/18
Human lung cancer  eIF4E  EGPI-1  Anticancer  Angiogenesis  
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun;  Fan, Junting;  Di, Guohu;  Guo, Chuanlong
Adobe PDF(8144Kb)  |  收藏  |  浏览/下载：172/0  |  提交时间：2021/04/21
PARP inhibitor  BRCA  Pancreatic cancer  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  收藏  |  浏览/下载：193/0  |  提交时间：2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：181/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载：153/0  |  提交时间：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
作者:  Guo, Chuanlong;  Hou, Yuzhen;  Yu, Xuemin;  Zhang, Fan;  Wu, Xiaochen;  Wu, Xianggen;  Wang, Lijun
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载：176/0  |  提交时间：2020/09/22
Apoptosis  eIF4F  ERK  MNK  A549 cells  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：283/0  |  提交时间：2020/03/20