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A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Adobe PDF(5208Kb)  |  收藏  |  浏览/下载：316/0  |  提交时间：2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载：225/0  |  提交时间：2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes  
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
作者:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling;  Li, Xiangqian;  Wang, Lijun;  Guo, Chuanlong;  Wu, Ning;  Shi, Dayong
Adobe PDF(2211Kb)  |  收藏  |  浏览/下载：255/0  |  提交时间：2019/08/20
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载：283/0  |  提交时间：2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：259/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 7, 页码: 4452-4469
作者:  Luo, Jiao;  Wu, Ning;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Wang, Baocheng;  Wang, Changhui;  Shi, Dayong
Adobe PDF(1638Kb)  |  收藏  |  浏览/下载：255/2  |  提交时间：2015/12/07
Anti-Angiogenic Properties of BDDPM, a Bromophenol from Marine Red Alga Rhodomela confervoides, with Multi Receptor Tyrosine Kinase Inhibition Effects 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 卷号: 16, 期号: 6, 页码: 13548-13560
作者:  Wang, Shuaiyu;  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Li, Xiangqian;  Liu, Shaofang;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2050Kb)  |  收藏  |  浏览/下载：238/1  |  提交时间：2015/12/07
Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 806-823
作者:  Wang, Li-Jun;  Wang, Shuai-Yu;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Wang, Bao-Cheng;  Luo, Jiao;  Yang, Meng;  Jin, Shui-Hua;  Shi, Da-Yong
Adobe PDF(1301Kb)  |  收藏  |  浏览/下载：243/0  |  提交时间：2015/06/15
Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl)-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating beta 1-Integrin/FAK Signaling 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 1010-1025
作者:  Wu, Ning;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Wang, Changhui;  Fu, Changqing;  Li, Jian;  Shi, Dayong
Adobe PDF(995Kb)  |  收藏  |  浏览/下载：228/1  |  提交时间：2015/06/15
Synthesis and biological evaluation of novel fluorinated anticancer agents incorporating the indolin-2-one moiety 期刊论文
RSC Advances, 2015, 卷号: 5, 期号: 111, 页码: 91795-91801
作者:  Wang, Shuai-Yu;  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Luo, Jiao;  Wang, Bao-Cheng;  Zhang, Ren-Shuai;  Xu, Qi;  Shi, Da-Yong
Adobe PDF(1588Kb)  |  收藏  |  浏览/下载：216/1  |  提交时间：2015/12/21