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A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：335/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：250/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
作者:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
Adobe PDF(1892Kb)  |  收藏  |  浏览/下载：213/0  |  提交时间：2017/09/30
Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
The design strategy of selective PTP1B inhibitors over TCPTP 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 16, 页码: 3343-3352
作者:  Li, XiangQian;  Wang, LiJun;  Shi, DaYong
Adobe PDF(2312Kb)  |  收藏  |  浏览/下载：192/1  |  提交时间：2016/12/05
Selectivity  Ptp1b Inhibitor  Tcptp  Diabetes  Design Strategy  
Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells 期刊论文
TUMOR BIOLOGY, 2015, 卷号: 36, 期号: 12, 页码: 9667-9676
作者:  Wu, Ning;  Liu, Jia;  Zhao, Xiangzhong;  Yan, Zhiyong;  Jiang, Bo;  Wang, Lijun;  Cao, Shousong;  Shi, Dayong;  Lin, Xiukun
Adobe PDF(1959Kb)  |  收藏  |  浏览/下载：249/1  |  提交时间：2016/02/05
Cardamonin  Glioblastoma Stem Cell  Stat3  Apoptosis  Temozolomide  Self-renewal  
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 7, 页码: 4452-4469
作者:  Luo, Jiao;  Wu, Ning;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Wang, Baocheng;  Wang, Changhui;  Shi, Dayong
Adobe PDF(1638Kb)  |  收藏  |  浏览/下载：254/2  |  提交时间：2015/12/07
Anti-Angiogenic Properties of BDDPM, a Bromophenol from Marine Red Alga Rhodomela confervoides, with Multi Receptor Tyrosine Kinase Inhibition Effects 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 卷号: 16, 期号: 6, 页码: 13548-13560
作者:  Wang, Shuaiyu;  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Li, Xiangqian;  Liu, Shaofang;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2050Kb)  |  收藏  |  浏览/下载：236/1  |  提交时间：2015/12/07
A New Furanone Isolated from a Marine-Derived Actinomycete M159 期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2015, 卷号: 51, 期号: 3, 页码: 480-482
作者:  Guo, Shuju;  Su, Hua;  Li, Xiancui;  Shi, Dayong;  Zhu, Xiaobin
Adobe PDF(133Kb)  |  收藏  |  浏览/下载：207/1  |  提交时间：2015/07/27
Marine-derived Actinomycetes  Furanone  
Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl)-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating beta 1-Integrin/FAK Signaling 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 1010-1025
作者:  Wu, Ning;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Wang, Changhui;  Fu, Changqing;  Li, Jian;  Shi, Dayong
Adobe PDF(995Kb)  |  收藏  |  浏览/下载：226/1  |  提交时间：2015/06/15
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao;  Shi, DY
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：311/1  |  提交时间：2014/07/17
Type 2 Diabetes Mellitus  Protein Tyrosine Phosphatase 1b  Bromophenol  Anti-diabetic Activities