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The ancient CgPEPCK-1, not CgPECK-2, evolved into a multifunctional molecule as an intracellular enzyme and extracellular PRR 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023, 卷号: 145, 页码: 13
作者:  Yin, Xiaoting;  Qiu, Limei;  Long, Dandan;  Lv, Zhao;  Liu, Qing;  Wang, Senyu;  Zhang, Weiqian;  Zhang, Kexin;  Xie, Mengxi
收藏  |  浏览/下载:48/0  |  提交时间:2023/12/13
PEPCK  Gene evolution and differentiation  PRR  Catalyzing enzyme  
Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:  Deng, Zhenzhen;  Wu, Ning;  Suo, Qishan;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
Adobe PDF(8782Kb)  |  收藏  |  浏览/下载:128/0  |  提交时间:2023/01/04
Capecitabine  Tumor microenvironment  Macrophages  TLR4  Fucoidan  
Integrative omics analysis highlights the immunomodulatory effects of the parasitic dinoflagellate hhematodinium on crustacean hemocytes 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2022, 卷号: 125, 页码: 35-47
作者:  Li, Meng;  Huang, Qian;  Lv, Xiaoyang;  Small, Hamish J.;  Li, Caiwen
Adobe PDF(7291Kb)  |  收藏  |  浏览/下载:176/0  |  提交时间:2022/07/18
Parasitic dinoflagellates  Hematodinium  Crustacean  Innate immunity  Host-parasite interaction  Omics study  
microRNAs facilitate comprehensive responses of Bathymodiolinae mussel against symbiotic and nonsymbiotic bacteria stimulation 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2021, 卷号: 119, 页码: 420-431
作者:  Chen, Hao;  Wang, Minxiao;  Zhang, Huan;  Wang, Hao;  Zhou, Li;  Zhong, Zhaoshan;  Cao, Lei;  Lian, Chao;  Sun, Yan;  Li, Chaolun
Adobe PDF(5618Kb)  |  收藏  |  浏览/下载:316/1  |  提交时间:2022/01/05
Bathymodiolinae mussel  Pattern recognition receptor  Methane oxidation bacteria  Chemosynthetic ecosystem  miRNAs  Symbiosis  
Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 卷号: 297, 期号: 4, 页码: 12
作者:  Liu, Ge;  Liu, Rui;  Shan, Yeqi;  Sun, Chaomin
Adobe PDF(3926Kb)  |  收藏  |  浏览/下载:163/0  |  提交时间:2022/01/05
Identification of a Novel Pattern Recognition Receptor DM9 Domain Containing Protein 4 as a Marker for Pro-Hemocyte of Pacific Oyster Crassostrea gigas 期刊论文
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 11, 页码: 15
作者:  Jia, Zhihao;  Jiang, Shuai;  Wang, Mengqiang;  Wang, Xiudan;  Liu, Yu;  Lv, Zhao;  Song, Xiaorui;  Li, Yiqun;  Wang, Lingling;  Song, Linsheng
Adobe PDF(3525Kb)  |  收藏  |  浏览/下载:261/0  |  提交时间:2021/04/14
Crassostrea gigas  DM9 domain  pattern recognition  innate immune response  pro-hemocytes  
A Fish Galectin-8 Possesses Direct Bactericidal Activity 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 1, 页码: 15
作者:  Zhang, Tengfei;  Jiang, Shuai;  Sun, Li
Adobe PDF(6336Kb)  |  收藏  |  浏览/下载:200/0  |  提交时间:2021/04/21
galectin-8  Cynoglossus semilaevis  bacterial binding  bactericidal  immune defense  
A live attenuated Edwardsiella tarda vaccine induces immunological expression pattern in Japanese flounder (Paralichthys olivaceus) in the early phase of immunization 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2021, 卷号: 239, 页码: 12
作者:  Li, Xue-Peng;  Zhang, Jian
Adobe PDF(3532Kb)  |  收藏  |  浏览/下载:184/0  |  提交时间:2021/04/12
Paralichthys olivaceus  Transcriptome  Attenuated vaccine  Immune response  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:287/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
The Members of the Highly DiverseCrassostrea gigasIntegrin Family Cooperate for the Generation of Various Immune Responses 期刊论文
FRONTIERS IN IMMUNOLOGY, 2020, 卷号: 11, 页码: 22
作者:  Lv, Zhao;  Qiu, Limei;  Wang, Weilin;  Liu, Zhaoqun;  Liu, Qing;  Wang, Lingling;  Song, Linsheng
Adobe PDF(7265Kb)  |  收藏  |  浏览/下载:302/0  |  提交时间:2020/09/25
Crassostrea gigas  integrin family  immune function  ECM ligand binding  functional division and cooperation