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Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
Authors:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
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type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
Authors:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
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Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
Authors:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
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DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
Authors:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling;  Li, Xiangqian;  Wang, Lijun;  Guo, Chuanlong;  Wu, Ning;  Shi, Dayong
Adobe PDF(2211Kb)  |  Favorite  |  View/Download:9/0  |  Submit date:2019/08/20