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Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression 期刊论文
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:  Song, Wen;  Xing, Ronge;  Yang, Haoyue;  Liu, Song;  Yu, Huahua;  Li, Pengcheng
收藏  |  浏览/下载：38/0  |  提交时间：2023/11/30
type 2 diabetes mellitus (T2DM)  eumelanin  hypoglycemic activity  antioxidant activity  antidepressant activity  
Preparation and Antioxidant Activity of Chitosan Dimers with Different Sequences 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 7, 页码: 15
作者:  Hao, Wentong;  Li, Kecheng;  Ma, Yuzhen;  Li, Rongfeng;  Xing, Ronge;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2007Kb)  |  收藏  |  浏览/下载：293/0  |  提交时间：2021/08/17
chitosan dimers  sequence  separation  biological method  antioxidant activity  
Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Xu, Fei;  Marletaz, Ferdinand;  Gavriouchkina, Daria;  Liu, Xiao;  Sauka-Spengler, Tatjana;  Zhang, Guofan;  Holland, Peter W. H.
Adobe PDF(1722Kb)  |  收藏  |  浏览/下载：179/0  |  提交时间：2021/12/07
Thallium in aquatic environments and the factors controlling Tl behavior 期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2021, 页码: 16
作者:  Zhuang, Wen;  Song, Jinming
Adobe PDF(854Kb)  |  收藏  |  浏览/下载：138/0  |  提交时间：2021/12/07
Thallium  Redox  Biogeochemical characteristics  Pollution  Water environment  Sediment  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：191/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Effect of chronic exposure to microplastic fibre ingestion in the sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 209, 页码: 8
作者:  Mohsen, Mohamed;  Zhang, Libin;  Sun, Lina;  Lin, Chenggang;  Wang, Qing;  Liu, Shilin;  Sun, Jinchun;  Yang, Hongsheng
Adobe PDF(1306Kb)  |  收藏  |  浏览/下载：264/0  |  提交时间：2021/04/14
Microplastic fibres  Toxicity mechanism  Biomarker  Antioxidant  Growth rate  Immunity  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：282/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 13
作者:  Li, Zhi;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(1107Kb)  |  收藏  |  浏览/下载：237/0  |  提交时间：2021/04/12
glycocalyx  vascular complications  diabetes  endothelial dysfunction  enzyme  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：163/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：295/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability