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Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Adobe PDF(4835Kb)  |  Favorite  |  View/Download:26/0  |  Submit date:2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
海洋溴酚化合物抗肿瘤活性筛选及作用机制研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:  郭传龙
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海洋溴酚化合物  抗肿瘤  Eif4e  Parp-1抑制剂  
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
Authors:  Guo, Chuanlong;  Wang, Lijun;  Li, Xinxue;  Wang, Shuaiyu;  Yu, Xuemin;  Xu, Kuo;  Zhao, Yue;  Luo, Jiao;  Li, Xiangqian;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:15/0  |  Submit date:2019/08/28
Cyclization Reaction of Acyl Thiourea Chitosan: Enhanced Antifungal Properties via Structural Optimization 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 13
Authors:  Qin, Yukun;  Liu, Weixiang;  Xing, Ronge;  Liu, Song;  Li, Kecheng;  Li, Pengcheng
Adobe PDF(5247Kb)  |  Favorite  |  View/Download:10/0  |  Submit date:2019/08/21
synthesis  1,2,4-triazolyl  acyl thiourea  chitosan  antifungal activity