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A hypervariable immunoglobulin superfamily member from Crassostrea gigas functions as pattern recognition receptor with opsonic activity 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 卷号: 86, 页码: 96-108
Authors:  Liu, Dongyang;  Yi, Qilin;  Wu, Yichen;  Lu, Guangxia;  Gong, Changhao;  Song, Xiaorui;  Sun, Jiejie;  Qu, Chen;  Liu, Conghui;  Wang, Lingling;  Song, Linsheng
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Crassostrea gigas  IgSF  Opsonin  Recombination  Balancing selection  
A DM9-containing protein from oyster Crassostrea gigas (CgDM9CP-2) serves as a multipotent pattern recognition receptor 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 卷号: 84, 页码: 315-326
Authors:  Liu, Yu;  Zhang, Peng;  Wang, Weilin;  Dong, Miren;  Wang, Min;  Gong, Changhao;  Jia, Zhihao;  Liu, Zhaoqun;  Zhang, Anguo;  Wang, Lingling;  Song, Linsheng
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Crassostrea gigas  DM9 domain  Pattern recognition receptor  Mannose binding  Antimicrobial activities  
Transcriptomic and Quantitative Proteomic Analyses Provide Insights Into the Phagocytic Killing of Hemocytes in the Oyster Crassostrea gigas 期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 页码: 17
Authors:  Jiang, Shuai;  Qiu, Limei;  Wang, Lingling;  Jia, Zhihao;  Lv, Zhao;  Wang, Mengqiang;  Liu, Conghui;  Xu, Jiachao;  Song, Linsheng
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Crassostrea gigas  transcriptome  quantitative proteome  phagocyte  oxidative killing  lysosome  cathepsin L  
The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 页码: 205-212
Authors:  Wang, Mengqiang;  Wang, Lingling;  Jia, Zhihao;  Yi, Qilin;  Song, Linsheng
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Chlamys farreri  Innate immunity  TLR signaling pathway  
The versatile functions of LRR-only proteins in mollusk Chlamys farreri 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 77, 页码: 188-199
Authors:  Wang, Mengqiang;  Wang, Lingling;  Jia, Zhihao;  Wang, Xiudan;  Yi, Qilin;  Zhao, Lv;  Song, Linsheng
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Immunomodulation  Innate Immunity  Pattern Recognition  Scallop  
DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum 期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8, 页码: 17
Authors:  Jiang, Shuai;  Wang, Lingling;  Huang, Mengmeng;  Jia, Zhihao;  Weinert, Tobias;  Warkentin, Eberhard;  Liu, Conghui;  Song, Xiaorui;  Zhang, Haixia;  Witt, Jennifer;  Qiu, Limei;  Peng, Guohong;  Song, Linsheng
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innate immunity  pattern recognition receptor  DM9 domain  crystal structure  mannose binding  phagocytosis  
Two novel LRR and Ig domain-containing proteins from oyster Crassostrea gigas function as pattern recognition receptors and induce expression of cytokines 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 70, 页码: 308-318
Authors:  Wang, Xiudan;  Wang, Mengqiang;  Xu, Qingsong;  Xu, Jiachao;  Lv, Zhao;  Wang, Lingling;  Song, Linsheng
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Crassostrea Gigas  Leucine-rich Repeat Domain  Immunoglobulin Domain  Pattern Recognition Receptor  Innate Immunity  
The RNA-seq analysis suggests a potential multi-component complement system in oyster Crassostrea gigas 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 76, 页码: 209-219
Authors:  Wang, Lingling;  Zhang, Huan;  Wang, Leilei;  Zhang, Daoxiang;  Lv, Zhao;  Liu, Zhaoqun;  Wang, Weilin;  Zhou, Zhi;  Qiu, Limei;  Wang, Hao;  Li, Jun;  Song, Linsheng
Adobe PDF(1948Kb)  |  Favorite  |  View/Download:42/0  |  Submit date:2018/01/11
Crassostrea Gigas  Complement Related Prrs  Serine Protease Domain-containing Proteins  C3  C3 Receptor-like Proteins  
The fragmentation mechanism and immune-protective effect of CfTEP in the scallop Chlamys farreri 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 76, 页码: 220-228
Authors:  Xue, Zhuang;  Wang, Leilei;  Liu, Zhaoqun;  Wang, Weilin;  Liu, Chang;  Song, Xiaorui;  Wang, Lingling;  Song, Linsheng
Adobe PDF(1682Kb)  |  Favorite  |  View/Download:47/0  |  Submit date:2018/01/11
Chlamys Farreri  Thioester-containing Proteins  Cleavage Sites  Innate Immunity  Methylamine  
The first CUB-domain containing serine protease from Chlamys farreri which might be involved in larval development and immune response 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 76, 页码: 163-168
Authors:  Yang, Chuanyan;  Wang, Leilei;  Zhang, Huan;  Yi, Qilin;  Wang, Lingling;  Wang, Hao;  Song, Linsheng
Adobe PDF(820Kb)  |  Favorite  |  View/Download:37/0  |  Submit date:2018/01/11
Chlamys Farreri  Cubsp  Immune Response  Larval Development