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Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:  Li, Zhi;  Wu, Ning;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
收藏  |  浏览/下载：1/0  |  提交时间：2024/04/07
diabetic vascular complication  glycocalyx  insulin resistance  LMWF  NEU2  
Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：176/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：275/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:  Li, Fengli;  Wang, Jing;  Wu, Ning;  Zhang, Hua;  Li, Zheng;  Wei, Ning
Adobe PDF(1665Kb)  |  收藏  |  浏览/下载：207/0  |  提交时间：2020/03/20
5-FU  Drug resistance  STAT3  Hepatocellular carcinoma  MCL-1  PUMA  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：287/0  |  提交时间：2020/03/20
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载：225/0  |  提交时间：2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes  
CS5931, A Novel Marine Polypeptide, Inhibits Migration and Invasion of Cancer Cells Via Interacting with Enolase 1 期刊论文
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2018, 卷号: 13, 期号: 3, 页码: 360-367
作者:  Su, Shuonan;  Xu, Huanli;  Chen, Xiaoliang;  Qiao, Gan;  Farooqi, Ammad A.;  Tian, Ye;  Yuan, Ru;  Liu, Xiaohui;  Li, Cong;  Li, Xiao;  Wu, Ning;  Lin, Xiukun
Adobe PDF(6130Kb)  |  收藏  |  浏览/下载：265/0  |  提交时间：2019/08/23
Enolase1  migration and invasion  protein-protein interaction  recombinant CS5931  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：337/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Interaction between granulin A and enolase 1 attenuates the migration and invasion of human hepatoma cells 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 18, 页码: 30305-30316
作者:  Chen, Xiaoliang;  Xu, Huanli;  Wu, Ning;  Liu, Xiujun;  Qiao, Gan;  Su, Shuonan;  Tian, Ye;  Yuan, Ru;  Li, Cong;  Liu, Xiaohui;  Lin, Xiukun
Adobe PDF(6244Kb)  |  收藏  |  浏览/下载：264/0  |  提交时间：2017/09/29
Enolase 1  Granulin a  Invasion  Migration  Protein-protein Interaction  
Pokemon promotes the invasiveness of hepatocellular carcinoma by enhancing MEF2D transcription 期刊论文
HEPATOLOGY INTERNATIONAL, 2016, 卷号: 10, 期号: 3, 页码: 493-500
作者:  Kong, Jing;  Liu, Xiaoping;  Li, Xiangqian;  Wu, Jinsheng;  Wu, Ning;  Chen, Jun;  Fang, Fang
Adobe PDF(1462Kb)  |  收藏  |  浏览/下载：210/0  |  提交时间：2016/08/25
Pokemon  Mef2d  Hcc