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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载:191/0  |  提交时间:2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2683Kb)  |  收藏  |  浏览/下载:241/0  |  提交时间:2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
New nanomicelle curcumin formulation for ocular delivery: improved stability, solubility, and ocular anti-inflammatory treatment 期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 卷号: 43, 期号: 11, 页码: 1846-1857
作者:  Li, Mengshuang;  Xin, Meng;  Guo, Chuanlong;  Lin, Guiming;  Wu, Xianggen
Adobe PDF(2898Kb)  |  收藏  |  浏览/下载:187/0  |  提交时间:2018/01/11
Curcumin  Stability  Polyvinyl caprolactam-Polyvinyl Acetatepolyethylene Glycol Graft Copolymer (Pvcl-pva-peg)  Nanomicelle  Ocular Drug Delivery  
The Acaricidal Activity of Venom from the Jellyfish Nemopilema nomurai against the Carmine Spider Mite Tetranychus cinnabarinus 期刊论文
TOXINS, 2016, 卷号: 8, 期号: 6
作者:  Yu, Huahua;  Yue, Yang;  Dong, Xiangli;  Li, Rongfeng;  Li, Pengcheng
Adobe PDF(873Kb)  |  收藏  |  浏览/下载:368/1  |  提交时间:2016/09/19
Acaricidal Activity  Jellyfish  Nemopilema Nomurai  Venom  
Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2014, 卷号: 25, 期号: 11, 页码: 1154-1160
作者:  Liu, Jia;  Zheng, Lanhong;  Ma, Leina;  Wang, Bin;  Zhao, Youguang;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:237/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Akt  Cancer Prevention  Natural Compounds  
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways 期刊论文
ONCOLOGY REPORTS, 2014, 卷号: 32, 期号: 2, 页码: 567-572
作者:  Liu, Jia;  Zheng, Lanhong;  Zhong, Jiateng;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:209/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Cancer  Mammalian Target Of Rapamycin  C-jun N-terminal Kinase  
Oleanolic Acid Induces Metabolic Adaptation in Cancer Cells by Activating the AMP-Activated Protein Kinase Pathway 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 24, 页码: 5528-5537
作者:  Liu, Jia;  Zheng, Lanhong;  Wu, Ning;  Ma, Leina;  Zhong, Jiateng;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(4102Kb)  |  收藏  |  浏览/下载:229/0  |  提交时间:2015/06/11
Aerobic Glycolysis  Ampk  Metabolism  Oleanolic Acid  
两种天然产物抗肿瘤作用的分子机制 学位论文
, 北京: 中国科学院研究生院, 2014
作者:  刘佳
Adobe PDF(5241Kb)  |  收藏  |  浏览/下载:413/1  |  提交时间:2014/08/12
齐墩果酸  海兔素  抗肿瘤活性  代谢  耐药  
重组萨氏海鞘多肽CS5931抗血管生成活性研究 学位论文
, 北京: 中国科学院研究生院, 2014
作者:  刘格
Adobe PDF(1917Kb)  |  收藏  |  浏览/下载:278/0  |  提交时间:2014/08/11
重组多肽cs5931  抗血管生成  斑马鱼  Huvecs  Vegf  Mmps  
Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91606
作者:  Liu, Jia;  Wu, Ning;  Ma, Leina;  Liu, Ming;  Liu, Ge;  Zhang, Yuyan;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载:214/0  |  提交时间:2015/06/11