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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：189/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2683Kb)  |  收藏  |  浏览/下载：234/0  |  提交时间：2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
New nanomicelle curcumin formulation for ocular delivery: improved stability, solubility, and ocular anti-inflammatory treatment 期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 卷号: 43, 期号: 11, 页码: 1846-1857
作者:  Li, Mengshuang;  Xin, Meng;  Guo, Chuanlong;  Lin, Guiming;  Wu, Xianggen
Adobe PDF(2898Kb)  |  收藏  |  浏览/下载：185/0  |  提交时间：2018/01/11
Curcumin  Stability  Polyvinyl caprolactam-Polyvinyl Acetatepolyethylene Glycol Graft Copolymer (Pvcl-pva-peg)  Nanomicelle  Ocular Drug Delivery  
The Acaricidal Activity of Venom from the Jellyfish Nemopilema nomurai against the Carmine Spider Mite Tetranychus cinnabarinus 期刊论文
TOXINS, 2016, 卷号: 8, 期号: 6
作者:  Yu, Huahua;  Yue, Yang;  Dong, Xiangli;  Li, Rongfeng;  Li, Pengcheng
Adobe PDF(873Kb)  |  收藏  |  浏览/下载：361/1  |  提交时间：2016/09/19
Acaricidal Activity  Jellyfish  Nemopilema Nomurai  Venom  
Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 60, 页码: 48822-48834
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(1045Kb)  |  收藏  |  浏览/下载：217/1  |  提交时间：2015/07/27
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载：262/0  |  提交时间：2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2014, 卷号: 25, 期号: 11, 页码: 1154-1160
作者:  Liu, Jia;  Zheng, Lanhong;  Ma, Leina;  Wang, Bin;  Zhao, Youguang;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载：236/0  |  提交时间：2015/06/11
Oleanolic Acid  Autophagy  Akt  Cancer Prevention  Natural Compounds  
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways 期刊论文
ONCOLOGY REPORTS, 2014, 卷号: 32, 期号: 2, 页码: 567-572
作者:  Liu, Jia;  Zheng, Lanhong;  Zhong, Jiateng;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载：209/0  |  提交时间：2015/06/11
Oleanolic Acid  Autophagy  Cancer  Mammalian Target Of Rapamycin  C-jun N-terminal Kinase  
Oleanolic Acid Induces Metabolic Adaptation in Cancer Cells by Activating the AMP-Activated Protein Kinase Pathway 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 24, 页码: 5528-5537
作者:  Liu, Jia;  Zheng, Lanhong;  Wu, Ning;  Ma, Leina;  Zhong, Jiateng;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(4102Kb)  |  收藏  |  浏览/下载：228/0  |  提交时间：2015/06/11
Aerobic Glycolysis  Ampk  Metabolism  Oleanolic Acid  
Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91606
作者:  Liu, Jia;  Wu, Ning;  Ma, Leina;  Liu, Ming;  Liu, Ge;  Zhang, Yuyan;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载：211/0  |  提交时间：2015/06/11