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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载：3/0  |  提交时间：2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
CRISPR/Cas9-mediated gene mutation of EcIAG leads to sex reversal in the male ridgetail white prawn Exopalaemon carinicauda 期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2023, 卷号: 14, 页码: 11
作者:  Miao, Miao;  Li, Shihao;  Yuan, Jianbo;  Liu, Peipei;  Fang, Xiaochen;  Zhang, Chengsong;  Zhang, Xiaojun;  Li, Fuhua
Adobe PDF(17439Kb)  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/04/07
insulin-like androgenic gland hormone  Exopalaemon carinicauda  CRISPR/Cas9  sex reversal  gene editing  
LysM-containing proteins function in the resistance of Litopenaeus vannamei against Vibrio parahaemolyticus infection 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023, 卷号: 148, 页码: 9
作者:  Miao, Miao;  Li, Shihao;  Yu, Yang;  Li, Fuhua
Adobe PDF(4037Kb)  |  收藏  |  浏览/下载：93/0  |  提交时间：2023/12/13
Lysin motif  Litopenaeus vannamei  Binding activity  V. parahaemolyticus  SNPs  
Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification 期刊论文
GENOMICS, 2023, 卷号: 115, 期号: 6, 页码: 13
作者:  Ma, Yuzhen;  Li, Jie;  Yu, Huahua;  Teng, Lichao;  Geng, Hao;  Li, Rongfeng;  Xing, Ronge;  Liu, Song;  Li, Pengcheng
Adobe PDF(5440Kb)  |  收藏  |  浏览/下载：114/0  |  提交时间：2023/11/30
Nemopilema nomurai  Pacific biosciences  Oxford Nanopore Technologies  Venom  Jellyfish dermatitis  
Autophagy contributes to increase the content of intracellular free amino acids in hard clam (Mercenaria mercenaria) during prolonged exposure to hypersaline environments 期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:  Zhou, Cong;  Yang, Mei-jie;  Hu, Zhi;  Zou, Yan;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Song, Hao;  Zhang, Tao
Adobe PDF(5375Kb)  |  收藏  |  浏览/下载：148/1  |  提交时间：2023/11/30
Hyposalinity  Hypersalinity  Transcriptome  Autophagy  Free amino acids  
Synergistic modulation of neuroendocrine-inflammation pathway by microRNAs facilitates intertidal adaptation of molluscs 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 142, 页码: 10
作者:  Chen, Hao;  Wang, Lin;  Wang, Lingling;  Zhang, Huan;  Wang, Hao;  Song, Linsheng
Adobe PDF(6028Kb)  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/04/07
Inflammation response  Calmodulin  Nitrite oxide  Tumor necrosis factor  miRNAs  Aerial exposure  
Genome-wide mapping of regulatory variants for temperature- and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in Crassostrea ariakensis 期刊论文
ENVIRONMENTAL RESEARCH, 2023, 卷号: 236, 页码: 10
作者:  Zhang, Kexin;  Yang, Qi;  Du, Mingyang;  Zhang, Ziyan;  Wang, Wei;  Zhang, Guofan;  Li, Ao;  Li, Li
Adobe PDF(4626Kb)  |  收藏  |  浏览/下载：72/0  |  提交时间：2023/12/13
Temperature and salinity  Adaptation  Genotype-by-environment interaction  Gene expression  Cis-andtrans-eQTL  Crassostrea ariakensis  
Population genetic structure and implication for adaptive differentiation of the snail (Gastropoda, Provannidae) in deep-sea chemosynthetic ecosystems 期刊论文
ZOOLOGICA SCRIPTA, 2023, 页码: 15
作者:  Zhang, Yu;  Cheng, Jiao;  Sha, Zhongli;  Hui, Min
Adobe PDF(5970Kb)  |  收藏  |  浏览/下载：99/0  |  提交时间：2023/11/30
adaptive evolution  chemosynthetic ecosystem  gastropod  population genetics  RAD-seq  
Time-Course and Tissue-Specific Molecular Responses to Acute Thermal Stress in Japanese Mantis Shrimp Oratosquilla oratoria 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 15, 页码: 18
作者:  Zhang, Liwen;  Sha, Zhongli;  Cheng, Jiao
收藏  |  浏览/下载：68/0  |  提交时间：2023/12/13
climate change  acute heat stress  crustacean  thermal sensitivity  transcriptomics  
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 249, 页码: 10
作者:  Huo, Da;  Su, Fang;  Yang, Hongsheng;  Sun, Lina
收藏  |  浏览/下载：49/0  |  提交时间：2023/11/16
Thermal stress  Stress response  Defense mechanism  Extracellular vesicles  MicroRNA  Echinoderm