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The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载:283/0  |  提交时间:2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
CS5931, A Novel Marine Polypeptide, Inhibits Migration and Invasion of Cancer Cells Via Interacting with Enolase 1 期刊论文
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2018, 卷号: 13, 期号: 3, 页码: 360-367
作者:  Su, Shuonan;  Xu, Huanli;  Chen, Xiaoliang;  Qiao, Gan;  Farooqi, Ammad A.;  Tian, Ye;  Yuan, Ru;  Liu, Xiaohui;  Li, Cong;  Li, Xiao;  Wu, Ning;  Lin, Xiukun
Adobe PDF(6130Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2019/08/23
Enolase1  migration and invasion  protein-protein interaction  recombinant CS5931  
Interaction between granulin A and enolase 1 attenuates the migration and invasion of human hepatoma cells 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 18, 页码: 30305-30316
作者:  Chen, Xiaoliang;  Xu, Huanli;  Wu, Ning;  Liu, Xiujun;  Qiao, Gan;  Su, Shuonan;  Tian, Ye;  Yuan, Ru;  Li, Cong;  Liu, Xiaohui;  Lin, Xiukun
Adobe PDF(6244Kb)  |  收藏  |  浏览/下载:265/0  |  提交时间:2017/09/29
Enolase 1  Granulin a  Invasion  Migration  Protein-protein Interaction  
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载:263/0  |  提交时间:2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2014, 卷号: 25, 期号: 11, 页码: 1154-1160
作者:  Liu, Jia;  Zheng, Lanhong;  Ma, Leina;  Wang, Bin;  Zhao, Youguang;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:237/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Akt  Cancer Prevention  Natural Compounds  
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways 期刊论文
ONCOLOGY REPORTS, 2014, 卷号: 32, 期号: 2, 页码: 567-572
作者:  Liu, Jia;  Zheng, Lanhong;  Zhong, Jiateng;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:209/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Cancer  Mammalian Target Of Rapamycin  C-jun N-terminal Kinase  
p38 MAPK Signaling Mediates Mitochondrial Apoptosis in Cancer Cells Induced by Oleanolic Acid 期刊论文
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 卷号: 15, 期号: 11, 页码: 4519-4525
作者:  Liu, Jia;  Wu, Ning;  Ma, Lei-Na;  Zhong, Jia-Teng;  Liu, Ge;  Zheng, Lan-Hong;  Lin, Xiu-Kun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao, Peoples R China.
Adobe PDF(1193Kb)  |  收藏  |  浏览/下载:224/0  |  提交时间:2015/06/11
Oleanolic Acid  Apoptosis  P38 Mapk  Cancer  Ros  
Targeting cellular apoptotic pathway with peptides from marine organisms 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2013, 卷号: 1836, 期号: 1, 页码: 42-48
作者:  Zheng, Lanhong;  Lin, Xiukun;  Wu, Ning;  Liu, Ming;  Zheng, Yuan;  Sheng, Jun;  Ji, Xiaofeng;  Sun, Mi;  Lin, XK
Adobe PDF(440Kb)  |  收藏  |  浏览/下载:323/0  |  提交时间:2014/07/17
Apoptosis  Marine Organisms  Peptides