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Low molecular weight fucoidan and its fractions inhibit renal epithelial mesenchymal transition induced by TGF-beta 1 or FGF-2 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 105, 页码: 1482-1490
作者:  Li, Xinpeng;  Li, Xiaohong;  Zhang, Quanbin;  Zhao, Tingting
Adobe PDF(1196Kb)  |  收藏  |  浏览/下载:296/1  |  提交时间:2018/01/11
Low Molecular Weight Fucoidan  Renal Fibrosis  Epithelial-mesenchymal Transition  
Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 105, 页码: 1526-1531
作者:  Jin, Weihua;  Liu, Ge;  Zhong, Weihong;  Sun, Chaomin;  Zhang, Quanbin
Adobe PDF(734Kb)  |  收藏  |  浏览/下载:250/0  |  提交时间:2018/01/11
Sargassum Thunbergii  Anti-complement Activities  Anti-tumour Activities  
Polysaccharides and their depolymerized fragments from Costaria costata: Molecular weight and sulfation-dependent anticoagulant and FGF/FGFR signal activating activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 105, 页码: 1511-1518
作者:  Hou, Ningning;  Zhang, Meng;  Xu, Yingjie;  Sun, Zhongmin;  Wang, Jing;  Zhang, Lijuan;  Zhang, Quanbin
Adobe PDF(3973Kb)  |  收藏  |  浏览/下载:293/0  |  提交时间:2018/01/11
Costaria Costata  Polysaccharide  Structure  Anticoagulant  Fibroblast Growth Factor (Fgf)  Fibroblast Growth Factor Receptor (Fgfr)  
Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 61, 页码: 104057-104071
作者:  Kuang, Shan;  Liu, Ge;  Cao, Ruobing;  Zhang, Linlin;  Yu, Qiang;  Sun, Chaomin
Adobe PDF(7564Kb)  |  收藏  |  浏览/下载:241/0  |  提交时间:2018/04/02
Mansouramycin c  Marine-derived Isoquinolinequinone  Reactive Oxygen Species  Mitochondrial Permeability Transition Pore  Anticancer Drug  
Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1) 期刊论文
FRONTIERS IN MICROBIOLOGY, 2017, 卷号: 8
作者:  Yang, Na;  Sun, Chaomin;  Zhang, Lixin;  Liu, Jianguo;  Song, Fuhang
Adobe PDF(1396Kb)  |  收藏  |  浏览/下载:210/0  |  提交时间:2018/01/11
Hepatitis c Virus  Ns3 Helicase  Ns5b Rna-dependent Rna Polymerase  High Throughput  Inhibitor  
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载:281/0  |  提交时间:2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载:342/0  |  提交时间:2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
作者:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
Adobe PDF(1892Kb)  |  收藏  |  浏览/下载:219/0  |  提交时间:2017/09/30
Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
两种褐藻中多糖的分离分析及其生物活性研究 学位论文
, 青岛: 中国科学院海洋研究所, 2017
作者:  侯宁宁
Adobe PDF(2897Kb)  |  收藏  |  浏览/下载:322/3  |  提交时间:2017/05/31
莫氏马尾藻  多肋藻  多糖  抗凝血  成纤维细胞生长因子  
鱼类病原菌荧光假单胞菌的致病机制及宿主抗菌免疫因子的作用研究 学位论文
, 北京: 中国科学院大学, 2017
作者:  孙园园
Adobe PDF(5660Kb)  |  收藏  |  浏览/下载:309/5  |  提交时间:2017/06/06
荧光假单胞菌  毒力因子  疫苗  半滑舌鳎  抗感染