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Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 61, 页码: 104057-104071
作者:  Kuang, Shan;  Liu, Ge;  Cao, Ruobing;  Zhang, Linlin;  Yu, Qiang;  Sun, Chaomin
Adobe PDF(7564Kb)  |  收藏  |  浏览/下载:241/0  |  提交时间:2018/04/02
Mansouramycin c  Marine-derived Isoquinolinequinone  Reactive Oxygen Species  Mitochondrial Permeability Transition Pore  Anticancer Drug  
孕激素及其受体在大菱鲆精子发生过程中的作用研究 学位论文
, 北京: 中国科学院大学, 2017
作者:  丰程程
Adobe PDF(5092Kb)  |  收藏  |  浏览/下载:326/1  |  提交时间:2018/04/16
生长期+繁殖期+孕激素+孕激素受体+大菱鲆  
A Novel Vascular Endothelial Growth Factor Receptor Participates in White Spot Syndrome Virus Infection in Litopenaeus vannamei 期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8
作者:  Li, Shihao;  Wang, Zhiwei;  Li, Fuhua;  Yu, Kuijie;  Xiang, Jianhai
Adobe PDF(2551Kb)  |  收藏  |  浏览/下载:253/1  |  提交时间:2018/01/11
Vegfr  White Spot Syndrome Virus  Immune Response  Protein Interaction  Signaling Pathway  
Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress 期刊论文
G3-GENES GENOMES GENETICS, 2017, 卷号: 7, 期号: 11, 页码: 3681-3692
作者:  Huo, Da;  Sun, Lina;  Li, Xiaoni;  Ru, Xiaoshang;  Liu, Shilin;  Zhang, Libin;  Xing, Lili;  Yang, Hongsheng
Adobe PDF(1525Kb)  |  收藏  |  浏览/下载:270/1  |  提交时间:2018/01/11
Mirna  Sea Cucumber  Hypoxia Stress  Respiratory Tree  Illumina Deep Sequencing  
Insights into deep-sea adaptations and host-symbiont interactions: A comparative transcriptome study on Bathymodiolus mussels and their coastal relatives 期刊论文
MOLECULAR ECOLOGY, 2017, 卷号: 26, 期号: 19, 页码: 5133-5148
作者:  Zheng, Ping;  Wang, Minxiao;  Li, Chaolun;  Sun, Xiaoqing;  Wang, Xiaocheng;  Sun, Yan;  Sun, Song
Adobe PDF(1098Kb)  |  收藏  |  浏览/下载:397/0  |  提交时间:2018/01/11
Bathymodiolin  Deep-sea Adaptation  Immune  Lysosome  Symbiosis  Transcriptome  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载:344/0  |  提交时间:2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Transcriptome, antioxidant enzyme activity and histopathology analysis of hepatopancreas from the white shrimp Litopenaeus vannamei fed with aflatoxin 131(AFB1) 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 74, 页码: 69-81
作者:  Zhao, Wei;  Wang, Lei;  Liu, Mei;  Jiang, Keyong;  Wang, Mengqiang;  Yang, Guang;  Qi, Cancan;  Wang, Baojie
Adobe PDF(1592Kb)  |  收藏  |  浏览/下载:272/0  |  提交时间:2017/10/09
Litopenaeus Vannamei  Hepatopancreas  Aflatoxin B1  Transcriptome  Enzyme Activity  Histopathology  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载:311/0  |  提交时间:2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
Glycogen synthase kinase-3 (GSK3) regulates TNF production and haemocyte phagocytosis in the immune response of Chinese mitten crab Eriocheir sinensis 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 73, 页码: 144-155
作者:  Li, Xiaowei;  Jia, Zhihao;  Wang, Weilin;  Wang, Lingling;  Liu, Zhaoqun;  Yang, Bin;  Jia, Yunke;  Song, Xiaorui;  Yi, Qilin;  Qiu, Limei;  Song, Linsheng
Adobe PDF(2787Kb)  |  收藏  |  浏览/下载:315/1  |  提交时间:2017/07/10
Eriocheir Sinensis  Glycogen Synthase Kinase 3  Innate Immunity  Tnf-alpha Production  Phagocytosis  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载:260/0  |  提交时间:2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability