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Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:  Deng, Zhenzhen;  Wu, Ning;  Suo, Qishan;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
Adobe PDF(8782Kb)  |  收藏  |  浏览/下载：127/0  |  提交时间：2023/01/04
Capecitabine  Tumor microenvironment  Macrophages  TLR4  Fucoidan  
Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 215, 页码: 253-261
作者:  Cui, Meiyu;  Li, Xiaohong;  Geng, Lihua;  Wu, Ning;  Wang, Jing;  Deng, Zhenzhen;  Li, Zhi;  Zhang, Quanbin
收藏  |  浏览/下载：155/0  |  提交时间：2022/08/17
Fucoidan  Saccharina japonica  Scavenger receptor  Macrophage  SR-A  CD36  LOX-1  Immunomodulatory  
Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：170/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Purification, characterization and immunostimulatory activity of a novel exopolysaccharide from Bacillus sp. H5 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 189, 页码: 649-656
作者:  Wei, Maosheng;  Geng, Lihua;  Wang, Qingchi;  Yue, Yang;  Wang, Jing;  Wu, Ning;  Wang, Xiaoqing;  Sun, Chaomin;  Zhang, Quanbin
Adobe PDF(2757Kb)  |  收藏  |  浏览/下载：195/0  |  提交时间：2021/12/01
Exopolysaccharide  Characteristics  Immunostimulatory effects  
Degradation of different molecular weight fucoidans and their inhibition of TGF-beta 1 induced epithelial-mesenchymal transition in mouse renal tubular epithelial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 151, 页码: 545-553
作者:  Li, Xiaosong;  Wu, Ning;  Chen, Yongqiang;  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Qin, Yimin;  Zhang, Quanbin
Adobe PDF(2869Kb)  |  收藏  |  浏览/下载：173/0  |  提交时间：2020/09/23
Degradation  Fucoidan  Epithelial-mesenchymal transition  Kidney fibrosis  
Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 304-314
作者:  Wang, Jing;  Zhang, Quanbin;  Li, Shuang;  Chen, Zhihang;  Tan, Jiaojiao;  Yao, Jianting;  Duan, Delin
Adobe PDF(2307Kb)  |  收藏  |  浏览/下载：162/0  |  提交时间：2020/09/23
Fucoidan  ECM-receptor interaction  Fibronectin  
Glucofucogalactan, a heterogeneous low-sulfated polysaccharide from Saccharina japonica and its bioactivity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 90-97
作者:  Geng, Lihua;  Zhang, Quanbin;  Wang, Jing;  Jin, Weihua;  Zhao, Tingting;  Hu, Weicheng
Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：278/0  |  提交时间：2019/08/21
Saccharina japonica  Heteropolysaccharide  Aristolochic acid  Immunomodulation  
The effect of different substitute groups and molecular weights of fucoidan on neuroprotective and anticomplement activity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 82-89
作者:  Liu, Huaide;  Wang, Jing;  Zhang, Quanbin;  Zhang, Hong
Adobe PDF(883Kb)  |  收藏  |  浏览/下载：263/0  |  提交时间：2019/08/21
Fucoidan derivatives  Molecular weights  Substitute group  Neuroprotective  Anticomplement  
Comparative study of the effect of different fucoidans from Sargassum maclurei and Saccharina japonica on FGFs/FGFR signaling activation in BaF3 cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 107, 页码: 2429-2435
作者:  Geng, Lihua;  Hou, Ningning;  Zhang, Meng;  Xu, Yingjie;  Zhang, Qi;  Wang, Jing;  Zhang, Lijuan;  Zhang, Quanbin
Adobe PDF(1308Kb)  |  收藏  |  浏览/下载：292/0  |  提交时间：2019/08/21
Fucoidan  Sulfated polysaccharides  Fibroblast growth factor (FGF)  Fibroblast growth factor receptor (FGFR)  
Polysaccharides and their depolymerized fragments from Costaria costata: Molecular weight and sulfation-dependent anticoagulant and FGF/FGFR signal activating activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 105, 页码: 1511-1518
作者:  Hou, Ningning;  Zhang, Meng;  Xu, Yingjie;  Sun, Zhongmin;  Wang, Jing;  Zhang, Lijuan;  Zhang, Quanbin
Adobe PDF(3973Kb)  |  收藏  |  浏览/下载：286/0  |  提交时间：2018/01/11
Costaria Costata  Polysaccharide  Structure  Anticoagulant  Fibroblast Growth Factor (Fgf)  Fibroblast Growth Factor Receptor (Fgfr)