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Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91606
作者:  Liu, Jia;  Wu, Ning;  Ma, Leina;  Liu, Ming;  Liu, Ge;  Zhang, Yuyan;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载：214/0  |  提交时间：2015/06/11
Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2013, 卷号: 33, 期号: 8, 页码: 756-765
作者:  Wei, Jianteng;  Liu, Ming;  Liu, Haizhou;  Wang, Hui;  Wang, Fengxia;  Zhang, Yuyan;  Han, Lijun;  Lin, Xiukun;  Lin, XK
Adobe PDF(2882Kb)  |  收藏  |  浏览/下载：279/0  |  提交时间：2014/07/17
Oleanolic Acid  Apoptosis  Ros  Mitochondrial Depolarization  Lysosomal Membrane Permeabilization  
Mere15, a novel polypeptide from Meretrix meretrix, inhibits adhesion, migration and invasion of human lung cancer A549 cells via down-regulating MMPs 期刊论文
PHARMACEUTICAL BIOLOGY, 2013, 卷号: 51, 期号: 2, 页码: 145-151
作者:  Wang, Hui;  Wei, Jianteng;  Wu, Ning;  Liu, Ming;  Wang, Cuicui;  Zhang, Yuyan;  Wang, Fengxia;  Liu, Haizhou;  Lin, Xiukun;  Lin, XK
Adobe PDF(924Kb)  |  收藏  |  浏览/下载：320/1  |  提交时间：2014/07/17
Anticancer  Cancer Metastasis  Transwell Assay  Gelatin Zymography  Rt-pcr  
Induction of Apoptosis, G(0)/G(1) Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus 期刊论文
MARINE DRUGS, 2012, 卷号: 10, 期号: 11, 页码: 2596-2607
作者:  Liu, Ming;  Zhao, Xiangzhong;  Zhao, Jin;  Xiao, Lin;  Liu, Haizhou;  Wang, Cuicui;  Cheng, Linyou;  Wu, Ning;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
Adobe PDF(25326Kb)  |  收藏  |  浏览/下载：270/0  |  提交时间：2013/09/24
Meretrix Meretrix Linnaeus  Mere15  Apoptosis  Anticancer  
Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells 期刊论文
ONCOLOGY REPORTS, 2012, 卷号: 28, 期号: 4, 页码: 1339-1345
作者:  Wei, Jianteng;  Liu, Haizhou;  Liu, Ming;  Wu, Ning;  Zhao, Jin;  Xiao, Lin;  Han, Lijun;  Chu, Edward;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
Adobe PDF(762Kb)  |  收藏  |  浏览/下载：307/0  |  提交时间：2013/09/24
Apoptosis  Oleanolic Acid  5-fluorouracil  Pancreatic Cancer Cells  Synergism  
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文
EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450
作者:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning;  Zheng, Lanhong;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
Adobe PDF(697Kb)  |  收藏  |  浏览/下载：250/0  |  提交时间：2013/09/24
Meretrix Meretrix Linnaeus  Antitumor Polypeptide  Non-small-cell Lung Carcinoma  g(2)/m Phase Arrest  Apoptosis  
Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila 期刊论文
MOLECULES, 2011, 卷号: 16, 期号: 4, 页码: 2796-2801
作者:  Wang, Cui-Cui;  Liu, Hai-Zhou;  Liu, Ming;  Zhang, Yu-Yan;  Li, Tian-Tian;  Lin, Xiu-Kun
Adobe PDF(217Kb)  |  收藏  |  浏览/下载：220/0  |  提交时间：2012/07/03
Polyketide  Chromone  Indole Alkaloid  Mosher  Exophiala Pisciphila  
Phylogenetic analysis and screening of antimicrobial and cytotoxic activities of moderately halophilic bacteria isolated from the Weihai Solar Saltern (China) 期刊论文
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2010, 卷号: 26, 期号: 5, 页码: 879-888
作者:  Chen, Lei;  Wang, Guangyu;  Bu, Tong;  Zhang, Yunbin;  Wang, Yixin;  Liu, Ming;  Lin, Xiukun
Adobe PDF(245Kb)  |  收藏  |  浏览/下载：201/0  |  提交时间：2015/07/20
Moderately Halophilic Bacteria  Phylogenetic Analysis  Antimicrobial Activity  Cytotoxic Activity  Solar Saltern  
A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 卷号: 35, 期号: 4, 页码: 805-812
作者:  Ning, Xuanxuan;  Zhao, Jianmin;  Zhang, Yuyan;  Cao, Subing;  Liu, Ming;  Ling, Peixue;  Lin, Xiukun
Adobe PDF(351Kb)  |  收藏  |  浏览/下载：198/0  |  提交时间：2010/12/22
Meretrix Meretrix Linnaeus  Anti-tumor Protein  Cytotoxicity  Cell Membrane Permeability  Cell Cycle  Tubulin Polymerization  Apoptosis