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Oleanolic Acid Induces Metabolic Adaptation in Cancer Cells by Activating the AMP-Activated Protein Kinase Pathway 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 24, 页码: 5528-5537
作者:  Liu, Jia;  Zheng, Lanhong;  Wu, Ning;  Ma, Leina;  Zhong, Jiateng;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(4102Kb)  |  收藏  |  浏览/下载：231/0  |  提交时间：2015/06/11
Aerobic Glycolysis  Ampk  Metabolism  Oleanolic Acid  
Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91606
作者:  Liu, Jia;  Wu, Ning;  Ma, Leina;  Liu, Ming;  Liu, Ge;  Zhang, Yuyan;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(1769Kb)  |  收藏  |  浏览/下载：214/0  |  提交时间：2015/06/11
Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2013, 卷号: 33, 期号: 8, 页码: 756-765
作者:  Wei, Jianteng;  Liu, Ming;  Liu, Haizhou;  Wang, Hui;  Wang, Fengxia;  Zhang, Yuyan;  Han, Lijun;  Lin, Xiukun;  Lin, XK
Adobe PDF(2882Kb)  |  收藏  |  浏览/下载：278/0  |  提交时间：2014/07/17
Oleanolic Acid  Apoptosis  Ros  Mitochondrial Depolarization  Lysosomal Membrane Permeabilization  
Mere15, a novel polypeptide from Meretrix meretrix, inhibits adhesion, migration and invasion of human lung cancer A549 cells via down-regulating MMPs 期刊论文
PHARMACEUTICAL BIOLOGY, 2013, 卷号: 51, 期号: 2, 页码: 145-151
作者:  Wang, Hui;  Wei, Jianteng;  Wu, Ning;  Liu, Ming;  Wang, Cuicui;  Zhang, Yuyan;  Wang, Fengxia;  Liu, Haizhou;  Lin, Xiukun;  Lin, XK
Adobe PDF(924Kb)  |  收藏  |  浏览/下载：320/1  |  提交时间：2014/07/17
Anticancer  Cancer Metastasis  Transwell Assay  Gelatin Zymography  Rt-pcr  
Induction of Apoptosis, G(0)/G(1) Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus 期刊论文
MARINE DRUGS, 2012, 卷号: 10, 期号: 11, 页码: 2596-2607
作者:  Liu, Ming;  Zhao, Xiangzhong;  Zhao, Jin;  Xiao, Lin;  Liu, Haizhou;  Wang, Cuicui;  Cheng, Linyou;  Wu, Ning;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
Adobe PDF(25326Kb)  |  收藏  |  浏览/下载：270/0  |  提交时间：2013/09/24
Meretrix Meretrix Linnaeus  Mere15  Apoptosis  Anticancer  
Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells 期刊论文
ONCOLOGY REPORTS, 2012, 卷号: 28, 期号: 4, 页码: 1339-1345
作者:  Wei, Jianteng;  Liu, Haizhou;  Liu, Ming;  Wu, Ning;  Zhao, Jin;  Xiao, Lin;  Han, Lijun;  Chu, Edward;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
Adobe PDF(762Kb)  |  收藏  |  浏览/下载：307/0  |  提交时间：2013/09/24
Apoptosis  Oleanolic Acid  5-fluorouracil  Pancreatic Cancer Cells  Synergism  
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文
EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450
作者:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning;  Zheng, Lanhong;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
Adobe PDF(697Kb)  |  收藏  |  浏览/下载：250/0  |  提交时间：2013/09/24
Meretrix Meretrix Linnaeus  Antitumor Polypeptide  Non-small-cell Lung Carcinoma  g(2)/m Phase Arrest  Apoptosis  
Phylogenetic analysis and screening of antimicrobial and cytotoxic activities of moderately halophilic bacteria isolated from the Weihai Solar Saltern (China) 期刊论文
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2010, 卷号: 26, 期号: 5, 页码: 879-888
作者:  Chen, Lei;  Wang, Guangyu;  Bu, Tong;  Zhang, Yunbin;  Wang, Yixin;  Liu, Ming;  Lin, Xiukun
Adobe PDF(245Kb)  |  收藏  |  浏览/下载：201/0  |  提交时间：2015/07/20
Moderately Halophilic Bacteria  Phylogenetic Analysis  Antimicrobial Activity  Cytotoxic Activity  Solar Saltern  
A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 卷号: 35, 期号: 4, 页码: 805-812
作者:  Ning, Xuanxuan;  Zhao, Jianmin;  Zhang, Yuyan;  Cao, Subing;  Liu, Ming;  Ling, Peixue;  Lin, Xiukun
Adobe PDF(351Kb)  |  收藏  |  浏览/下载：198/0  |  提交时间：2010/12/22
Meretrix Meretrix Linnaeus  Anti-tumor Protein  Cytotoxicity  Cell Membrane Permeability  Cell Cycle  Tubulin Polymerization  Apoptosis