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The cholinergic and adrenergic autocrine signaling Pathway Mediates immunomodulation in Oyster Crassostrea gigas 期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9
Authors:  Liu, Zhaoqun;  Wang, Lingling;  Lv, Zhao;  Zhou, Zhi;  Wang, Weilin;  Li, Meijia;  Yi, Qilin;  Qiu, Limei;  Song, Linsheng
Adobe PDF(1957Kb)  |  Favorite  |  View/Download:81/0  |  Submit date:2018/04/02
Crassostrea Gigas  Autocrine/paracrine  Hemocyte  Neurotransmitter  Membrane Receptor  Immune Regulation  
Transcriptomic analysis of oyster Crassostrea gigas larvae illustrates the response patterns regulated by catecholaminergic system upon acute heat and bacterial stress 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 73, 页码: 52-60
Authors:  Liu, Zhaoqun;  Wang, Lingling;  Zhou, Zhi;  Liu, Yu;  Dong, Miren;  Wang, Weilin;  Song, Xiaorui;  Wang, Mengqiang;  Gao, Qiang;  Song, Linsheng
Adobe PDF(1355Kb)  |  Favorite  |  View/Download:62/0  |  Submit date:2017/07/10
Crassostrea Gigas Larvae  Transcriptomic Analysis  Acute Heat And Bacterial Stress  Catecholaminergic System  Immunomodulation  
A norepinephrine-responsive miRNA directly promotes CgHSP90AA1 expression in oyster haemocytes during desiccation 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 64, 页码: 297-307
Authors:  Chen, Hao;  Xin, Lusheng;  Song, Xiaorui;  Wang, Lin;  Wang, Weilin;  Liu, Zhaoqun;  Zhang, Huan;  Wang, Lingling;  Zhou, Zhi;  Qiu, Limei;  Song, Linsheng
Adobe PDF(1873Kb)  |  Favorite  |  View/Download:77/0  |  Submit date:2017/07/10
Desiccation  Norepinephrine  Hsp90  Mirna-mediated Gene Promotion  
The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas 期刊论文
OPEN BIOLOGY, 2017, 卷号: 7, 期号: 1
Authors:  Liu, Zhaoqun;  Zhou, Zhi;  Jiang, Qiufen;  Wang, Lingling;  Yi, Qilin;  Qiu, Limei;  Song, Linsheng
Adobe PDF(937Kb)  |  Favorite  |  View/Download:66/0  |  Submit date:2017/03/27
Crassostrea Gigas  Neuroendocrine Immunomodulatory Axis  Circulating Haemocyte  Membrane Receptor  Immune Regulation  
The cholinergic immune regulation mediated by a novel muscarinic acetylcholine receptor through TNF pathway in oyster Crassostrea gigas 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2016, 卷号: 65, 页码: 139-148
Authors:  Liu, Zhaoqun;  Zhou, Zhi;  Wang, Lingling;  Dong, Wenjing;  Qiu, Limei;  Song, Linsheng
Adobe PDF(2774Kb)  |  Favorite  |  View/Download:61/1  |  Submit date:2016/12/05
Crassostrea Gigas  Acetylcholine  Muscarinic Acetylcholine Receptor  Tnf Pathway  Immune Regulation  
CgA1AR-1 acts as an alpha-1 adrenergic receptor in oyster Crassostrea gigas mediating both cellular and humoral immune response 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 58, 页码: 50-58
Authors:  Liu, Zhaoqun;  Zhou, Zhi;  Wang, Lingling;  Qiu, Limei;  Zhang, Huan;  Wang, Hao;  Song, Linsheng
Adobe PDF(2766Kb)  |  Favorite  |  View/Download:60/1  |  Submit date:2017/03/21
Crassostrea Gigas  Norepinephrine  Alpha-1 Adrenergic Receptor  Tnf Pathway  Immune Regulation  
An invertebrate-specific miRNA targeted the ancient cholinergic neuroendocrine system of oyster 期刊论文
OPEN BIOLOGY, 2016, 卷号: 6, 期号: 8
Authors:  Chen, Hao;  Zhou, Zhi;  Wang, Lingling;  Wang, Hao;  Liu, Rui;  Zhang, Huan;  Song, Linsheng
Adobe PDF(952Kb)  |  Favorite  |  View/Download:71/0  |  Submit date:2016/11/22
Mirna  Mir-2 Family  Choline Transporter-like  Protein  Acetylcholine  Cholinergic System  Immunomodulation  
The neuroendocrine-immune regulatory network characterized as simple structure but complex function in oyster Crassostrea gigas 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 53, 页码: 81-81
Authors:  Wang, Lingling;  Liu, Zhaoqun;  Zhou, Zhi;  Song, Linsheng
Adobe PDF(53Kb)  |  Favorite  |  View/Download:26/0  |  Submit date:2016/09/19
Crassostrea Gigas  Tnf  Neurotransmitter  Regulatory Network  Immune Response  Cytokines  Transcription Factors  
The simple neuroendocrine-immune regulatory network in oyster Crassostrea gigas mediates complex functions 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:  Liu, Zhaoqun;  Wang, Lingling;  Zhou, Zhi;  Sun, Ying;  Wang, Mengqiang;  Wang, Hao;  Hou, Zhanhui;  Gao, Dahai;  Gao, Qiang;  Song, Linsheng
Adobe PDF(1574Kb)  |  Favorite  |  View/Download:114/0  |  Submit date:2016/09/21
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation 期刊论文
BMC GENOMICS, 2015, 卷号: 16, 期号: 942, 页码: 1-14
Authors:  Chen, Hao;  Wang, Lingling;  Zhou, Zhi;  Hou, Zhanhui;  Liu, Zhaoqun;  Wang, Weilin;  Gao, Dahai;  Gao, Qiang;  Wang, Mengqiang;  Song, Linsheng
Adobe PDF(2421Kb)  |  Favorite  |  View/Download:126/0  |  Submit date:2015/12/27
Oyster  Neurimmir  Acetylcholine  Norepinephrine  Immunomodulation  Neural-endocrine-immune System