IOCAS-IR

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H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:  Li, Fengli;  Wang, Jing;  Wu, Ning;  Zhang, Hua;  Li, Zheng;  Wei, Ning
Adobe PDF(1665Kb)  |  收藏  |  浏览/下载:229/0  |  提交时间:2020/03/20
5-FU  Drug resistance  STAT3  Hepatocellular carcinoma  MCL-1  PUMA  
Transcriptome and Gene Coexpression Network Analyses of Two Wild Populations Provides Insight into the High-Salinity Adaptation Mechanisms of Crassostrea ariakensis 期刊论文
MARINE BIOTECHNOLOGY, 2019, 卷号: 21, 期号: 5, 页码: 596-612
作者:  Liu, Xingyu;  Li, Li;  Li, Ao;  Li, Yingxiang;  Wang, Wei;  Zhang, Guofan
Adobe PDF(3289Kb)  |  收藏  |  浏览/下载:315/0  |  提交时间:2020/01/03
High-salinity adaptation  Wild populations  Larvae transcriptome  Weighted gene correlation network analysis  Crassostrea ariakensis  
IKK epsilon-like plays an important role in the innate immune signaling of the Pacific oyster (Crassostrea gigas) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 93, 页码: 551-558
作者:  Huang, Baoyu;  Tang, Xueying;  Zhang, Linlin;  Li, Li;  Wang, Wei;  Liu, Mingkun;  Zhang, Guofan
Adobe PDF(2123Kb)  |  收藏  |  浏览/下载:315/0  |  提交时间:2020/01/03
Oyster  Innate immunity  IKKe  TBK1  NF-kappa B  IRF  
Transcriptome and Gene Coexpression Network Analyses of Two Wild Populations Provides Insight into the High-Salinity Adaptation Mechanisms of Crassostrea ariakensis (vol 21, pg 596, 2019) 期刊论文
MARINE BIOTECHNOLOGY, 2019, 卷号: 21, 期号: 5, 页码: 613-613
作者:  Liu, Xingyu;  Li, Li;  Li, Ao;  Li, Yingxiang;  Wang, Wei;  Zhang, Guofan
Adobe PDF(93Kb)  |  收藏  |  浏览/下载:385/0  |  提交时间:2020/01/03
Thermotolerance Divergence Revealed by the Physiological and Molecular Responses in Two Oyster Subspecies of Crassostrea gigas in China 期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10, 页码: 15
作者:  Ghaffari, Hamze;  Wang, Wei;  Li, Ao;  Zhang, Guofan;  Li, Li
Adobe PDF(3100Kb)  |  收藏  |  浏览/下载:342/0  |  提交时间:2020/01/03
thermal tolerance  heart rate  metabolism  physiological performance  adaptive variation  
Hemolymph C1qDC promotes the phagocytosis of oyster Crassostrea gigas hemocytes by interacting with the membrane receptor beta-integrin 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 98, 页码: 42-53
作者:  Lv, Zhao;  Wang, Lingling;  Jia, Zhihao;  Sun, Jiejie;  Wang, Weilin;  Liu, Zhaoqun;  Qiu, Limei;  Wang, Mengqiang;  Song, Linsheng
Adobe PDF(1932Kb)  |  收藏  |  浏览/下载:323/0  |  提交时间:2019/08/29
Phagocytosis  C1qDC  Opsonization  beta-Integrin  Oyster Crassostrea gigas  
The Enhanced Immune Protection in Chinese Mitten Crab Eriocheir sinensis Against the Second Exposure to Bacteria Aeromonas hydrophila 期刊论文
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: 10, 页码: 12
作者:  Wang, Jingjing;  Yang, Bin;  Wang, Weilin;  Song, Xiaorui;  Jiang, Qiufen;  Qiu, Limei;  Wang, Lingling;  Song, Linsheng
Adobe PDF(2588Kb)  |  收藏  |  浏览/下载:294/0  |  提交时间:2020/01/03
immune priming  Eriocheir sinensis  Aeromonas hydrophila  phagocytosis  immune protection  
RNAi based transcriptome suggests genes potentially regulated by HSF1 in the Pacific oyster Crassostrea gigas under thermal stress 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 期号: 1, 页码: 15
作者:  Liu, Youli;  Li, Li;  Huang, Baoyu;  Wang, Wei;  Zhang, Guofan
Adobe PDF(3527Kb)  |  收藏  |  浏览/下载:307/0  |  提交时间:2019/11/14
Crassostrea gigas  Heat shock  HSP  HSF1  Regulatory  RNA interference  Transcriptome  WGCNA  
Evolutionary trade-offs between baseline and plastic gene expression in two congeneric oyster species 期刊论文
BIOLOGY LETTERS, 2019, 卷号: 15, 期号: 6, 页码: 5
作者:  Li, Ao;  Li, Li;  Wang, Wei;  Zhang, Guofan
Adobe PDF(542Kb)  |  收藏  |  浏览/下载:338/0  |  提交时间:2019/08/29
oyster  expression pattern  genetic adaptation  plasticity  evolutionary trade-off  genetic assimilation  
The activated beta-integrin (Cg beta V) enhances RGD-binding and phagocytic capabilities of hemocytes in Crassostrea gigas 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 87, 页码: 638-649
作者:  Lv, Zhao;  Qiu, Limei;  Jia, Zhihao;  Wang, Weilin;  Liu, Zhaoqun;  Wang, Lingling;  Song, Linsheng
Adobe PDF(4860Kb)  |  收藏  |  浏览/下载:296/0  |  提交时间:2019/08/28
C. gigas  RGD-Binding  Integrin activation  Integrin-mediated phagocytosis