Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)

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	Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)
	Ji, Nai-Yun 1,2; Li, Xiao-Ming 1; Xie, Hua 3; Ding, Jian 3; Li, Ke 1,2; Ding, Lan-Ping 1; Wang, Bin-Gui1
	2008
发表期刊	HELVETICA CHIMICA ACTA
ISSN	0018-019X
卷号	91 期号:10 页码:1940-1946
文章类型	Article
摘要	Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC(50) values of 0.6 and 6.6 mu g/ml, respectively.; Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC50 values of 0.6 and 6.6 mu g/ml, respectively.
关键词	Radical-scavenging Activity Polysiphonia-urceolata Thyrsiferyl 23-acetate Sesquiterpenes Bromophenols Apoptosis Decumbens
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000261050300014
引用统计	被引频次：28[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/6282
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Inst Mat Med, Shanghai 201203, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Ji, Nai-Yun,Li, Xiao-Ming,Xie, Hua,et al. Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)[J]. HELVETICA CHIMICA ACTA,2008,91(10):1940-1946.
APA	Ji, Nai-Yun.,Li, Xiao-Ming.,Xie, Hua.,Ding, Jian.,Li, Ke.,...&Wang, Bin-Gui.(2008).Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae).HELVETICA CHIMICA ACTA,91(10),1940-1946.
MLA	Ji, Nai-Yun,et al."Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)".HELVETICA CHIMICA ACTA 91.10(2008):1940-1946.

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