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The chemical constituents from red alga Gymnogongrus flabelliformis Harv.
Yuan Zhaohui1; Han Lijun1; Su Hua1,4; Shi Dayong1; Sun Jie; Li Shuai2,3; Shi Jiangong2,3
2008-05-01
发表期刊CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN0254-4059
卷号26期号:2页码:190-192
文章类型Article
摘要Eight compounds were isolated from red alga Gymnogongrus flabelliformis Harv. In normal phase silica gel, Sephadex LH-20 gel column chromatography, reverse phase HPLC, and recrystallization. Based on MS and 1D NMR spectroscopic data, their structures were determined as: stigmast-4-en-3-one (I), cholest-4-en-3-one (II), cholesterol (III), uracil (IV), uridine (V), adenosine (VI), succinic acid (VII), and 5-hydroxy-4-methyl-5-pentyl-2,5-dihydro-furan-2-on (VIII). All of them were obtained from this species for the first time. Cytotoxicity of these compounds was screened using standard MTT method, but all the compounds were inactive (IC(50) > 10 mu g/ml).; Eight compounds were isolated from red alga Gymnogongrus flabelliformis Harv. In normal phase silica gel, Sephadex LH-20 gel column chromatography, reverse phase HPLC, and recrystallization. Based on MS and 1D NMR spectroscopic data, their structures were determined as: stigmast-4-en-3-one (I), cholest-4-en-3-one (II), cholesterol (III), uracil (IV), uridine (V), adenosine (VI), succinic acid (VII), and 5-hydroxy-4-methyl-5-pentyl-2,5-dihydro-furan-2-on (VIII). All of them were obtained from this species for the first time. Cytotoxicity of these compounds was screened using standard MTT method, but all the compounds were inactive (IC50 > 10 mu g/ml).
关键词Red Algae Gymnogongrus Flabelliformis Harv. Chemical Constituents Mtt Assay
学科领域Limnology ; Oceanography
DOI10.1007/s00343-008-0190-5
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000256416000011
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被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/6110
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 10005, Peoples R China
3.Peking Union Med Coll, Beijing 10005, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
第一作者单位中国科学院海洋研究所
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Yuan Zhaohui,Han Lijun,Su Hua,et al. The chemical constituents from red alga Gymnogongrus flabelliformis Harv.[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2008,26(2):190-192.
APA Yuan Zhaohui.,Han Lijun.,Su Hua.,Shi Dayong.,Sun Jie.,...&Shi Jiangong.(2008).The chemical constituents from red alga Gymnogongrus flabelliformis Harv..CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,26(2),190-192.
MLA Yuan Zhaohui,et al."The chemical constituents from red alga Gymnogongrus flabelliformis Harv.".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 26.2(2008):190-192.
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