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Steroids from green alga Chaetomorpha basiretorsa Setchell
Shi Dayong1; Fan Xiao1; Sun Jie1; Han Lijun1; Shi Jiangong2,3
2008-11-01
发表期刊CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN0254-4059
卷号26期号:4页码:415-418
文章类型Article
摘要Six steroids have been isolated from ethanolic extract of green alga Chaetomorpha basiretorsa Setchell by a combination of repeated normal phase silica gel and Sephadex LH-20 gel column chromatography as well as recrystallization. Using spectroscopic methods including MS and NMR, their structures were determined as beta-lawsaritol (1), saringosterol (2), 24-hydroperoxy-24-vinyl-cholesterol (3), beta-stigmasterol (4), stigmast-4-en-3 alpha, 6 beta-diol (5), 29-hydroxystigmasta-5, 24 (28)-dien-3 beta-ol (6). All these compounds were obtained from this genus for the first time and they were inactive (IC(50)> 10 mu g /ml) against KB, Bel-7402, PC-3M, Ketr 3 and MCF-7 cell lines.; Six steroids have been isolated from ethanolic extract of green alga Chaetomorpha basiretorsa Setchell by a combination of repeated normal phase silica gel and Sephadex LH-20 gel column chromatography as well as recrystallization. Using spectroscopic methods including MS and NMR, their structures were determined as beta-lawsaritol (1), saringosterol (2), 24-hydroperoxy-24-vinyl-cholesterol (3), beta-stigmasterol (4), stigmast-4-en-3 alpha, 6 beta-diol (5), 29-hydroxystigmasta-5, 24 (28)-dien-3 beta-ol (6). All these compounds were obtained from this genus for the first time and they were inactive (IC50 > 10 mu g /ml) against KB, Bel-7402, PC-3M, Ketr 3 and MCF-7 cell lines.
关键词Green Alga Chaetomorpha Basiretorsa Setchell Steroids
学科领域Limnology ; Oceanography
DOI10.1007/s00343-008-0415-7
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000262669100013
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/6088
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 10005, Peoples R China
3.Peking Union Med Coll, Beijing 10005, Peoples R China
第一作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Shi Dayong,Fan Xiao,Sun Jie,et al. Steroids from green alga Chaetomorpha basiretorsa Setchell[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2008,26(4):415-418.
APA Shi Dayong,Fan Xiao,Sun Jie,Han Lijun,&Shi Jiangong.(2008).Steroids from green alga Chaetomorpha basiretorsa Setchell.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,26(4),415-418.
MLA Shi Dayong,et al."Steroids from green alga Chaetomorpha basiretorsa Setchell".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 26.4(2008):415-418.
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