IOCAS-IR  > 实验海洋生物学重点实验室
Pharmacological and immunocytochemical investigation of the role of catecholamines on larval metamorphosis by beta-adrenergic-like receptor in the bivalve Meretrix meretrix
Wang, Guodong; Liu, Baozhong; Tang, Baojun; Zhang, Tao; Xiang, Jianhai
2006-08-31
发表期刊AQUACULTURE
ISSN0044-8486
卷号258期号:1-4页码:611-618
文章类型Article
摘要Catecholamines regulate several physiological processes in mollusks. Many pharmacological experiments have been conducted to determine the effects of adrenergic agonist and antagonist of catecholamine receptors on Meretrix meretrix metamorphosis. Results showed that adrenaline (AD) and noradrenaline (NA) had substantial effects (p < 0.05) on larval metamorphosis at concentrations ranging from 10 mu M to 100 mu M. 10 mu M beta-adrenergic receptor (AR) agonist isoproterenol showed the same inducement effect as that of NA and AD on metamorphosis, whereas the alpha-AR agonist phenylephrine had no significant effect at concentrations between 0.1 mu M and 100 mu M concentrations (p > 0.05). Furthermore, I mu M beta-AR antagonist propanolol, but not alpha-AR antagonist prazosin, depressed the larval metamorphosis induced by NA or AD. By immunocytochemistry, two cell bodies of beta-adrenergic-like receptor, C/A1, C/A2, were observed in the cerebral/apical ganglion of competent larvae. In addition, there were other immunoreactive dots near C/A1 and C/A2. The results of pharmacology and immunocytochemistry suggests that beta-adrenergic-like receptor located in the larval CNS, might play a considerable role in the larval metamorphosis of M meretrix by AD or NA. (c) 2006 Elsevier B.V. All rights reserved.; Catecholamines regulate several physiological processes in mollusks. Many pharmacological experiments have been conducted to determine the effects of adrenergic agonist and antagonist of catecholamine receptors on Meretrix meretrix metamorphosis. Results showed that adrenaline (AD) and noradrenaline (NA) had substantial effects (p < 0.05) on larval metamorphosis at concentrations ranging from 10 mu M to 100 mu M. 10 mu M beta-adrenergic receptor (AR) agonist isoproterenol showed the same inducement effect as that of NA and AD on metamorphosis, whereas the alpha-AR agonist phenylephrine had no significant effect at concentrations between 0.1 mu M and 100 mu M concentrations (p > 0.05). Furthermore, I mu M beta-AR antagonist propanolol, but not alpha-AR antagonist prazosin, depressed the larval metamorphosis induced by NA or AD. By immunocytochemistry, two cell bodies of beta-adrenergic-like receptor, C/A1, C/A2, were observed in the cerebral/apical ganglion of competent larvae. In addition, there were other immunoreactive dots near C/A1 and C/A2. The results of pharmacology and immunocytochemistry suggests that beta-adrenergic-like receptor located in the larval CNS, might play a considerable role in the larval metamorphosis of M meretrix by AD or NA. (c) 2006 Elsevier B.V. All rights reserved.
关键词Meretrix Meretrix Metamorphosis Catecholamine Adrenergic Receptor
学科领域Fisheries ; Marine & Freshwater Biology
DOI10.1016/j.aquaculture.2006.04.031
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000240252900070
引用统计
被引频次:31[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/5958
专题实验海洋生物学重点实验室
海洋生态与环境科学重点实验室
作者单位1.Acad Sinica, Inst Oceanol, Expt Marine Biol Lab, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Wang, Guodong,Liu, Baozhong,Tang, Baojun,et al. Pharmacological and immunocytochemical investigation of the role of catecholamines on larval metamorphosis by beta-adrenergic-like receptor in the bivalve Meretrix meretrix[J]. AQUACULTURE,2006,258(1-4):611-618.
APA Wang, Guodong,Liu, Baozhong,Tang, Baojun,Zhang, Tao,&Xiang, Jianhai.(2006).Pharmacological and immunocytochemical investigation of the role of catecholamines on larval metamorphosis by beta-adrenergic-like receptor in the bivalve Meretrix meretrix.AQUACULTURE,258(1-4),611-618.
MLA Wang, Guodong,et al."Pharmacological and immunocytochemical investigation of the role of catecholamines on larval metamorphosis by beta-adrenergic-like receptor in the bivalve Meretrix meretrix".AQUACULTURE 258.1-4(2006):611-618.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
wang-Pharmacological(319KB) 限制开放--浏览
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Guodong]的文章
[Liu, Baozhong]的文章
[Tang, Baojun]的文章
百度学术
百度学术中相似的文章
[Wang, Guodong]的文章
[Liu, Baozhong]的文章
[Tang, Baojun]的文章
必应学术
必应学术中相似的文章
[Wang, Guodong]的文章
[Liu, Baozhong]的文章
[Tang, Baojun]的文章
相关权益政策
暂无数据
收藏/分享
文件名: wang-Pharmacological and immunocytochemical investigation.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。