Reviews on The Immunological Function of Tetraspanins

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	Reviews on The Immunological Function of Tetraspanins
	Gui Lang; Wang Bing; Li Fu-Hua; Xiang Jian-Hai
	2008-11-01
发表期刊	PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN	1000-3282
卷号	35 期号:11 页码:1231-1238
文章类型	Review
摘要	Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.; Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.
关键词	Tetraspanins Immunity Virus Transmembrane 4 Superfamily Invertebrate
学科领域	Biochemistry & Molecular Biology ; Biophysics
收录类别	SCI
语种	英语
WOS记录号	WOS:000261290200003
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/5564
专题	实验海洋生物学重点实验室
作者单位	Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Gui Lang,Wang Bing,Li Fu-Hua,et al. Reviews on The Immunological Function of Tetraspanins[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2008,35(11):1231-1238.
APA	Gui Lang,Wang Bing,Li Fu-Hua,&Xiang Jian-Hai.(2008).Reviews on The Immunological Function of Tetraspanins.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,35(11),1231-1238.
MLA	Gui Lang,et al."Reviews on The Immunological Function of Tetraspanins".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 35.11(2008):1231-1238.

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