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Reviews on The Immunological Function of Tetraspanins
Gui Lang; Wang Bing; Li Fu-Hua; Xiang Jian-Hai
2008-11-01
Source PublicationPROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN1000-3282
Volume35Issue:11Pages:1231-1238
SubtypeReview
AbstractTetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.; Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.
KeywordTetraspanins Immunity Virus Transmembrane 4 Superfamily Invertebrate
Subject AreaBiochemistry & Molecular Biology ; Biophysics
Indexed BySCI
Language英语
WOS IDWOS:000261290200003
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Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/5564
Collection实验海洋生物学重点实验室
AffiliationChinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Gui Lang,Wang Bing,Li Fu-Hua,et al. Reviews on The Immunological Function of Tetraspanins[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2008,35(11):1231-1238.
APA Gui Lang,Wang Bing,Li Fu-Hua,&Xiang Jian-Hai.(2008).Reviews on The Immunological Function of Tetraspanins.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,35(11),1231-1238.
MLA Gui Lang,et al."Reviews on The Immunological Function of Tetraspanins".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 35.11(2008):1231-1238.
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