IOCAS-IR  > 海洋生物技术研发中心
Polysaccharides from Ulva pertusa (Chlorophyta) and preliminary studies on their antihyperlipidemia activity
Yu, PZ; Zhang, QB; Li, N; Xu, ZH; Wang, YM; Li, ZE
2003
发表期刊JOURNAL OF APPLIED PHYCOLOGY
ISSN0921-8971
卷号15期号:1页码:21-27
文章类型Article
摘要Polysaccharides from Ulva pertusa were isolated and prepared by extraction in hot water and precipitation by ethanol. The water-soluble polysaccharides were chemically well defined, containing 47.0% total carbohydrate, 23.2% uronic acids, 17.1% sulfate groups, 1.0% N and 29.9% ash. Gas chromatography analysis demonstrated that the neutral sugars were mainly composed of rhamnose, xylose and glucose and smaller amounts of mannose, galactose and arabinose. The FTIR and (13)C-NMR spectra indicated that basic repeating units of the polysaccharides were (beta-D-GlcpA-(1->4)-alpha-L-Rhap 3S) and (alpha-L-IdopA-(1->4)-alpha-L-Rhap 3S). Fifty ICR mice were used to study the effect of water-soluble polysaccharides from Ulva pertusa on the level of plasma lipids, with inositol niacinate as positive control. The results indicated that the polysaccharides significantly lowered the contents of plasma total cholesterol, low-density lipoprotein cholesterol, triglyceride and markedly increased the contents of serum high-density lipoprotein cholesterol, compared with the hyperlipidemia control group (p<0.01). Moreover, administration of polysaccharides significantly decreased the atherogenic index. The present results suggest that the polysaccharides from Ulva pertusa have great potential for preventing ischemic cardiovascular and cerebrovascular diseases.; Polysaccharides from Ulva pertusa were isolated and prepared by extraction in hot water and precipitation by ethanol. The water-soluble polysaccharides were chemically well defined, containing 47.0% total carbohydrate, 23.2% uronic acids, 17.1% sulfate groups, 1.0% N and 29.9% ash. Gas chromatography analysis demonstrated that the neutral sugars were mainly composed of rhamnose, xylose and glucose and smaller amounts of mannose, galactose and arabinose. The FTIR and C-13-NMR spectra indicated that basic repeating units of the polysaccharides were (beta-D-GlcpA-(1->4)-alpha-L-Rhap 3S) and (alpha-L-IdopA-(1->4)-alpha-L-Rhap 3S). Fifty ICR mice were used to study the effect of water-soluble polysaccharides from Ulva pertusa on the level of plasma lipids, with inositol niacinate as positive control. The results indicated that the polysaccharides significantly lowered the contents of plasma total cholesterol, low-density lipoprotein cholesterol, triglyceride and markedly increased the contents of serum high-density lipoprotein cholesterol, compared with the hyperlipidemia control group (p<0.01). Moreover, administration of polysaccharides significantly decreased the atherogenic index. The present results suggest that the polysaccharides from Ulva pertusa have great potential for preventing ischemic cardiovascular and cerebrovascular diseases.
关键词Antihyperlipidemia Effect Hyperlipidemia Polysaccharides Ulva Pertusa Ulvan
学科领域Biotechnology & Applied Microbiology ; Marine & Freshwater Biology
收录类别SCI
语种英语
WOS记录号WOS:000181768200003
引用统计
被引频次:114[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/3596
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Dept Chem, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Yu, PZ,Zhang, QB,Li, N,et al. Polysaccharides from Ulva pertusa (Chlorophyta) and preliminary studies on their antihyperlipidemia activity[J]. JOURNAL OF APPLIED PHYCOLOGY,2003,15(1):21-27.
APA Yu, PZ,Zhang, QB,Li, N,Xu, ZH,Wang, YM,&Li, ZE.(2003).Polysaccharides from Ulva pertusa (Chlorophyta) and preliminary studies on their antihyperlipidemia activity.JOURNAL OF APPLIED PHYCOLOGY,15(1),21-27.
MLA Yu, PZ,et al."Polysaccharides from Ulva pertusa (Chlorophyta) and preliminary studies on their antihyperlipidemia activity".JOURNAL OF APPLIED PHYCOLOGY 15.1(2003):21-27.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
yu-Polysaccharides f(411KB) 限制开放--浏览
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yu, PZ]的文章
[Zhang, QB]的文章
[Li, N]的文章
百度学术
百度学术中相似的文章
[Yu, PZ]的文章
[Zhang, QB]的文章
[Li, N]的文章
必应学术
必应学术中相似的文章
[Yu, PZ]的文章
[Zhang, QB]的文章
[Li, N]的文章
相关权益政策
暂无数据
收藏/分享
文件名: yu-Polysaccharides from Ulva.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。