| Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro | |
Wang, Jing1,2 ; Zhang, Quanbin1; Zhang, Zhongshan1,2; Zhang, Jingjing1,2; Li, Pengcheng1
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| 2009-03-01 | |
| 发表期刊 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| 卷号 | 44期号:2页码:170-174 |
| 文章类型 | Article |
| 摘要 | Three sulfated polysaccharide derivatives (phosphorylated and aminated fucoidan) were synthesized, and their potential antioxidant activities were investigated employing various established in vitro systems. Two methods were used in phosphorylation fucoidan: polyphosphoric acid and POCl(3) method. Aminated fucoidan was prepared using the epichlorohydrin and ammonia water. All fucoidan derivatives possessed considerable antioxidant activity, and exhibited stronger antioxidant ability than fucoidan in certain tests. The phosphorylated fucoidan showed stronger hydroxyl radical and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and reducing power. The mechanism on influence the antioxidant activity of samples of phosphate and amino group was indicated. (C) 2008 Elsevier B.V. All rights reserved.; Three sulfated polysaccharide derivatives (phosphorylated and aminated fucoidan) were synthesized, and their potential antioxidant activities were investigated employing various established in vitro systems. Two methods were used in phosphorylation fucoidan: polyphosphoric acid and POCl3 method. Aminated fucoidan was prepared using the epichlorohydrin and ammonia water. All fucoidan derivatives possessed considerable antioxidant activity, and exhibited stronger antioxidant ability than fucoidan in certain tests. The phosphorylated fucoidan showed stronger hydroxyl radical and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and reducing power. The mechanism on influence the antioxidant activity of samples of phosphate and amino group was indicated. (C) 2008 Elsevier B.V. All rights reserved. |
| 关键词 | Fucoidan Phosphorylated Aminated Antioxidant Activity |
| 学科领域 | Biochemistry & Molecular Biology |
| DOI | 10.1016/j.ijbiomac.2008.11.010 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000263927000009 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/3496 |
| 专题 | 海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,et al. Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2009,44(2):170-174. |
| APA | Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,Zhang, Jingjing,&Li, Pengcheng.(2009).Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,44(2),170-174. |
| MLA | Wang, Jing,et al."Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 44.2(2009):170-174. |
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