Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro

doi:10.1016/j.ijbiomac.2009.02.001

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	Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro
	Wang, Jing1,2 ; Wang, Feng3 ; Zhang, Quanbin 1; Zhang, Zhongshan 1,2; Shi, Xuelian 1,2; Li, Pengcheng1
	2009-06-01
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
卷号	44 期号:5 页码:379-384
文章类型	Article
摘要	Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. The benzoylated DFPS (PHDF) showed strongest scavenging activity on superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, however, DFPS exhibited greatest reducing power. Available data suggested that substituted groups of DFPS played an important role on antioxidant activity, and the mechanism on influence the antioxidant activity of samples of substituted group was indicated. (C) 2009 Elsevier B.V. All rights reserved.; Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. The benzoylated DFPS (PHDF) showed strongest scavenging activity on superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, however, DFPS exhibited greatest reducing power. Available data suggested that substituted groups of DFPS played an important role on antioxidant activity, and the mechanism on influence the antioxidant activity of samples of substituted group was indicated. (C) 2009 Elsevier B.V. All rights reserved.
关键词	Low Molecular Fucoidan Derivatives Antioxidant Activity
学科领域	Biochemistry & Molecular Biology
DOI	10.1016/j.ijbiomac.2009.02.001
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000266712500001
引用统计	被引频次：56[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/3492
专题	海洋生物技术研发中心海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Wei Fang Med Univ, Pharmaceut Lab, Weifang 261053, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wang, Jing,Wang, Feng,Zhang, Quanbin,et al. Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2009,44(5):379-384.
APA	Wang, Jing,Wang, Feng,Zhang, Quanbin,Zhang, Zhongshan,Shi, Xuelian,&Li, Pengcheng.(2009).Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,44(5),379-384.
MLA	Wang, Jing,et al."Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 44.5(2009):379-384.

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