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Vancomycin-functionalised Ag@TiO2 phototoxicity for bacteria
Wan, Yi; Zhang, Dun; Wang, Yi; Qi, Peng; Wu, Jiajia; Hou, Baorong
AbstractThis study reports on the synthesis of vancomycin (Van)-functionalised Ag@TiO2 nanoparticles and their enhanced bactericidal activities. Van-Ag@TiO2 nanoparticles were prepared by nanoparticle deposition and chemical cross-linking reactions. The catalysts showed high efficiency for the degradation of methylene blue under ultraviolet (UV) illumination. The photocatalytic inactivation of the sulphate-reducing bacteria, Desulfotomaculum, was also studied under UV light irradiation and in the dark using aqueous mixtures of Ag, Ag@SiO2, Ag@TiO2, and Van-Ag@TiO2. The Van-Ag@TiO2 nanoparticles showed a capacity to target Van-sensitive bacteria. They also effectively prevented bacterial cell growth through the functionalised nanoparticles under UV irradiation for 1 h. To investigate the specificity of the catalyst phototoxicity, a Van-resistant bacteria, Vibrio anguillarum, was used as the negative control. The results indicated that Van-Ag@TiO2 nanoparticles had a higher selective phototoxicity for Van-sensitive bacteria. Therefore, the antibiotic molecule-functionalised core-shell nanoparticles allow for selective photokilling of pathogenic bacteria. (C) 2010 Elsevier B.V. All rights reserved.
KeywordPhototoxicity Sulphate-reducing Bacteria Vancomycin Photocatalyst
Indexed BySCI
WOS IDWOS:000288102400037
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Cited Times:37[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
AffiliationChinese Acad Sci, Key Lab Corros Sci, Inst Oceanol, Qingdao 266071, Shandong, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wan, Yi,Zhang, Dun,Wang, Yi,et al. Vancomycin-functionalised Ag@TiO2 phototoxicity for bacteria[J]. JOURNAL OF HAZARDOUS MATERIALS,2011,186(1):306-312.
APA Wan, Yi,Zhang, Dun,Wang, Yi,Qi, Peng,Wu, Jiajia,&Hou, Baorong.(2011).Vancomycin-functionalised Ag@TiO2 phototoxicity for bacteria.JOURNAL OF HAZARDOUS MATERIALS,186(1),306-312.
MLA Wan, Yi,et al."Vancomycin-functionalised Ag@TiO2 phototoxicity for bacteria".JOURNAL OF HAZARDOUS MATERIALS 186.1(2011):306-312.
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