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Regioselective syntheses of sulfated porphyrans from Porphyra haitanensis and their antioxidant and anticoagulant activities in vitro
Zhang, Zhongshan1,2; Zhang, Quanbin1; Wang, Jing1,2; Song, Houfang1,2; Zhang, Hong1; Niu, Xizhen1
2010-03-17
发表期刊CARBOHYDRATE POLYMERS
卷号79期号:4页码:1124-1129
文章类型Article
摘要Porphyran extracted from Porphyra haitanensis is a sulfated polysaccharide, which possesses excellent antioxidant activities. In this study, we prepared porphyran and alkali-treated porphyran and their derivatives, sulfated porphyran. And then we evaluated their antioxidant and anticoagulant activities in vitro and characterized the relationship between activities and chemical characteristics. The activities were strongly dependant on the degree of sulfation and the position of sulfate. In this study, the antioxidant activities mainly depend on degree of substitution, and the anticoagulant activities mainly depend on the position of sulfate. Further studies are needed to improve our understanding of antioxidant and anticoagulant activities mechanism. (c) 2009 Elsevier Ltd. All rights reserved.
关键词Porphyran Sulfation Antioxidant Activity Anticoagulant Activities
DOI10.1016/j.carbpol.2009.10.055
收录类别SCI
语种英语
WOS记录号WOS:000275220500046
引用统计
被引频次:43[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/32811
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
第一作者单位中国科学院海洋研究所
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GB/T 7714
Zhang, Zhongshan,Zhang, Quanbin,Wang, Jing,et al. Regioselective syntheses of sulfated porphyrans from Porphyra haitanensis and their antioxidant and anticoagulant activities in vitro[J]. CARBOHYDRATE POLYMERS,2010,79(4):1124-1129.
APA Zhang, Zhongshan,Zhang, Quanbin,Wang, Jing,Song, Houfang,Zhang, Hong,&Niu, Xizhen.(2010).Regioselective syntheses of sulfated porphyrans from Porphyra haitanensis and their antioxidant and anticoagulant activities in vitro.CARBOHYDRATE POLYMERS,79(4),1124-1129.
MLA Zhang, Zhongshan,et al."Regioselective syntheses of sulfated porphyrans from Porphyra haitanensis and their antioxidant and anticoagulant activities in vitro".CARBOHYDRATE POLYMERS 79.4(2010):1124-1129.
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