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Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica
Wang, Jing1,2; Zhang, Quanbin1; Zhang, Zhongshan1,2; Song, Houfang1,2; Li, Pengcheng1
2010
发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷号46期号:1页码:6-12
文章类型Article
摘要A low molecular weight fucoidan (DFPS), obtained from the brown seaweed Laminaria japonica, was separated into three fractions by anion-exchange column chromatography. All three fractions (DF1, DF2, DF3) predominantly contained variety fucose, galactose and sulfate group. The antioxidant and anticoagulant activities of these fractions were investigated. The results showed that all fractions possessed considerable antioxidant activities, DF1 was most active. All samples inhibited coagulant in APTT, TT and PT assays obviously. Available data presented the content of sulfate group, the molar ratio of sulfate/fucose and sulfate/total sugar, and the molecular weight played an important role on antioxidant and anticoagulant activity. (C) 2009 Elsevier B.V. All rights reserved.
关键词Low Molecular Weight Fucoidan Laminaria Japonica Antioxidant Anticoagulant
DOI10.1016/j.ijbiomac.2009.10.015
收录类别SCI
语种英语
WOS记录号WOS:000274971900002
引用统计
被引频次:324[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/32770
专题海洋生物技术研发中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
第一作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,et al. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2010,46(1):6-12.
APA Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,Song, Houfang,&Li, Pengcheng.(2010).Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,46(1),6-12.
MLA Wang, Jing,et al."Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 46.1(2010):6-12.
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