Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp NJ6-3-1

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	Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp NJ6-3-1
	Zheng, L ; Yan, XJ ; Xu, JL ; Chen, HM ; Lin, W
	2005
发表期刊	APPLIED BIOCHEMISTRY AND MICROBIOLOGY
ISSN	0003-6838
卷号	41 期号:1 页码:29-33
文章类型	Article
摘要	Among marine bacteria isolated from the cytotoxic sponge Hymeniacidon perleve, one strain NJ6-3-1 classified as Pseudomonas sp. showed both cytotoxic and antimicrobial activities. Fatty acid analysis indicated that the bacterial strain consists mainly of C16:1, C16:0, C18:1, C18:0, C15:0, C14:0. One unusual 9,10-cyclopropane-C17:0 fatty acid and C26:0 also constitute major components, as well as the existence of squalene, the precursor of triterpenoids. The major metabolites in the culture broth were identified as alkaloids, including diketopiperazines and indole compounds, namely 3,6-diisopropylpiperazine-2,5-dione, 3-benzyl-3-isopropylpiperazine-2,5-dione, 3,6-bis-(2-methylpropyl)-piperazine-2,5-dione, indole-3-carboxaldehyde, indole-3-carboxylic acid methyl ester, indole-3-ethanol, and quinazoline-2,4-dione.; Among marine bacteria isolated from the cytotoxic sponge Hymeniacidon perleve, one strain NJ6-3-1 classified as Pseudomonas sp. showed both cytotoxic and antimicrobial activities. Fatty acid analysis indicated that the bacterial strain consists mainly of C16:1, C16:0, C18:1, C18:0, C15:0, C14:0. One unusual 9,10-cyclopropane-C17:0 fatty acid and C26:0 also constitute major components, as well as the existence of squalene, the precursor of triterpenoids. The major metabolites in the culture broth were identified as alkaloids, including diketopiperazines and indole compounds, namely 3,6-diisopropylpiperazine-2,5-dione, 3-benzyl-3-isopropylpiperazine-2,5-dione, 3,6-bis-(2-methylpropyl)-piperazine-2,5-dione, indole-3-carboxaldehyde, indole-3-carboxylic acid methyl ester, indole-3-ethanol, and quinazoline-2,4-dione.
关键词	Marine-bacteria Antimicrobial Activity Sponge Biosynthesis Diketopiperazines Metabolites Exposure Growth Acids
学科领域	Biotechnology & Applied Microbiology ; Microbiology
收录类别	SCI
语种	英语
WOS记录号	WOS:000226910300006
引用统计	被引频次：15[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/3170
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Grad Sch, Inst Oceanol, Qingdao 266071, Peoples R China 2.Ningbo Univ, Ningbo 315211, Peoples R China
推荐引用方式 GB/T 7714	Zheng, L,Yan, XJ,Xu, JL,et al. Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp NJ6-3-1[J]. APPLIED BIOCHEMISTRY AND MICROBIOLOGY,2005,41(1):29-33.
APA	Zheng, L,Yan, XJ,Xu, JL,Chen, HM,&Lin, W.(2005).Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp NJ6-3-1.APPLIED BIOCHEMISTRY AND MICROBIOLOGY,41(1),29-33.
MLA	Zheng, L,et al."Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp NJ6-3-1".APPLIED BIOCHEMISTRY AND MICROBIOLOGY 41.1(2005):29-33.

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