Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris | |
Tian Minqing1,3; Dai Haofu2; Li Xiaoming1; Wang Bingui1 | |
2009-06-01 | |
发表期刊 | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY |
ISSN | 0254-4059 |
卷号 | 27期号:2页码:288-296 |
文章类型 | Article |
摘要 | Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC(50) 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.; Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites. |
关键词 | Mangrove Sonneratia Caseolaris Chemical Constituents Cytotoxic Assay |
学科领域 | Limnology ; Oceanography |
DOI | 10.1007/s00343-009-9138-7 |
URL | 查看原文 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000267970300013 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/3022 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, State Key Lab Trop Crops Biotechnol, Haikou 571101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
第一作者单位 | 实验海洋生物学重点实验室 |
推荐引用方式 GB/T 7714 | Tian Minqing,Dai Haofu,Li Xiaoming,et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2009,27(2):288-296. |
APA | Tian Minqing,Dai Haofu,Li Xiaoming,&Wang Bingui.(2009).Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,27(2),288-296. |
MLA | Tian Minqing,et al."Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 27.2(2009):288-296. |
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