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Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
Tian Minqing1,3; Dai Haofu2; Li Xiaoming1; Wang Bingui1
2009-06-01
发表期刊CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN0254-4059
卷号27期号:2页码:288-296
文章类型Article
摘要Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC(50) 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.; Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 mu g/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.
关键词Mangrove Sonneratia Caseolaris Chemical Constituents Cytotoxic Assay
学科领域Limnology ; Oceanography
DOI10.1007/s00343-009-9138-7
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000267970300013
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被引频次:33[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/3022
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, State Key Lab Trop Crops Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
第一作者单位实验海洋生物学重点实验室
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Tian Minqing,Dai Haofu,Li Xiaoming,et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2009,27(2):288-296.
APA Tian Minqing,Dai Haofu,Li Xiaoming,&Wang Bingui.(2009).Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,27(2),288-296.
MLA Tian Minqing,et al."Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 27.2(2009):288-296.
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