Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus

doi:10.1021/acs.jnatprod.5b00004

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	Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus
	Li, Xiao-Dong1,2 ; Li, Xiao-Ming 1; Xu, Gang-Ming 1; Zhang, Peng1,2 ; Wang, Bin-Gui1
	2015-04-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
卷号	78 期号:4 页码:844-849
文章类型	Article
摘要	Three new phenolic bisabolane sesquiterpenes, peniciaculins A (1) and B (2) and (7S)-(-)-10-hydroxysydonic acid (3), together with a new nor-bisabolane derivative, 1-hydroxyboivinianin A (4), as well as six known bisabolanes (5-10), were identified from the culture of Penicillium aculeatum SD-321, a fungus isolated from deep-sea sediments. The structures of these compounds were mainly determined by analysis of spectroscopic data, and the absolute configurations of compounds 1-4 were established by comparing their ECD spectra with those of known analogues or by TDDFT-ECD calculations. Compound 1 represents the first example of a bisabolane analogue linked to a diphenyl ether moiety via an ether bond, while compound 2 appears to be the first dimeric bisabolane analogue where the two monomers are coupled to each other via an ester bond. The isolated compounds were evaluated for antimicrobial activity against 10 human and aquatic pathogenic bacteria and three plant-pathogenic fungi.
DOI	10.1021/acs.jnatprod.5b00004
收录类别	SCI
语种	英语
WOS记录号	WOS:000353665100032
引用统计	被引频次：70[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/26962
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Li, Xiao-Dong,Li, Xiao-Ming,Xu, Gang-Ming,et al. Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(4):844-849.
APA	Li, Xiao-Dong,Li, Xiao-Ming,Xu, Gang-Ming,Zhang, Peng,&Wang, Bin-Gui.(2015).Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus.JOURNAL OF NATURAL PRODUCTS,78(4),844-849.
MLA	Li, Xiao-Dong,et al."Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus".JOURNAL OF NATURAL PRODUCTS 78.4(2015):844-849.

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Antimicrobial Phenol（573KB）	期刊论文	出版稿	限制开放	ODC PDDL	浏览