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Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii
Zhang, Peng1,2; Li, Xiao-Ming1; Wang, Jia-Ning1,2; Li, Xin1,2; Wang, Bin-Gui1
2015-03-01
发表期刊CHINESE CHEMICAL LETTERS
卷号26期号:3页码:313-316
文章类型Article
摘要Two new prenylated indole alkaloids, namely, dihydrocarneamide A (1) and iso-notoamide B (2), were isolated from the marine-derived endophytic fungus Paecilomyces variotii EN-291. The structures of these metabolites were determined based on comprehensive spectral analysis, together with chiral HPLC analysis of the acidic hydrolysates. Unlike other prenylated indole alkaloids such as asperparalines, notoamides, and versicolamides, compounds 1 and 2 are the rare examples of C-5 prenylation, forming the fused dimethyldihydropyran ring at C-5 and C-6 of the indole ring. The cytotoxic activity of the isolated compounds was evaluated. (C) 2014 Bin-Gui Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved.
关键词Natural Products Indolediketopiperazine Marine Algal-derived Fungus Paecilomyces Variotii Cytotoxicity
DOI10.1016/j.cclet.2014.11.020
收录类别SCI
语种英语
WOS记录号WOS:000353089000012
引用统计
被引频次:34[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/25484
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位实验海洋生物学重点实验室
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GB/T 7714
Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,et al. Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii[J]. CHINESE CHEMICAL LETTERS,2015,26(3):313-316.
APA Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,Li, Xin,&Wang, Bin-Gui.(2015).Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii.CHINESE CHEMICAL LETTERS,26(3),313-316.
MLA Zhang, Peng,et al."Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii".CHINESE CHEMICAL LETTERS 26.3(2015):313-316.
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