Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii | |
Zhang, Peng1,2; Li, Xiao-Ming1; Wang, Jia-Ning1,2; Li, Xin1,2; Wang, Bin-Gui1 | |
2015-03-01 | |
发表期刊 | CHINESE CHEMICAL LETTERS |
卷号 | 26期号:3页码:313-316 |
文章类型 | Article |
摘要 | Two new prenylated indole alkaloids, namely, dihydrocarneamide A (1) and iso-notoamide B (2), were isolated from the marine-derived endophytic fungus Paecilomyces variotii EN-291. The structures of these metabolites were determined based on comprehensive spectral analysis, together with chiral HPLC analysis of the acidic hydrolysates. Unlike other prenylated indole alkaloids such as asperparalines, notoamides, and versicolamides, compounds 1 and 2 are the rare examples of C-5 prenylation, forming the fused dimethyldihydropyran ring at C-5 and C-6 of the indole ring. The cytotoxic activity of the isolated compounds was evaluated. (C) 2014 Bin-Gui Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved. |
关键词 | Natural Products Indolediketopiperazine Marine Algal-derived Fungus Paecilomyces Variotii Cytotoxicity |
DOI | 10.1016/j.cclet.2014.11.020 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000353089000012 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/25484 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
第一作者单位 | 实验海洋生物学重点实验室 |
推荐引用方式 GB/T 7714 | Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,et al. Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii[J]. CHINESE CHEMICAL LETTERS,2015,26(3):313-316. |
APA | Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,Li, Xin,&Wang, Bin-Gui.(2015).Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii.CHINESE CHEMICAL LETTERS,26(3),313-316. |
MLA | Zhang, Peng,et al."Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii".CHINESE CHEMICAL LETTERS 26.3(2015):313-316. |
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