Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis

doi:10.1016/j.gene.2014.12.048

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	Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis
	Song, Chengwen1,2 ; Cui, Zhaoxia 1,3; Hui, Min 1; Liu, Yuan 1; Li, Yingdong 1; Li, Xihong 1,2
	2015-03-01
发表期刊	GENE
卷号	558 期号:1 页码:88-98
文章类型	Article
摘要	The development of Eriocheir sinensis from the megalopa to the first juvenile crab undergoes brachyurization and a habitat transition from pelagic to benthic lifestyle. However, the molecular mechanism of this process is poorly understood in crabs. Using next-generation RNA sequencing, we identified 22,622 annotated unigenes and 1016 differentially expressed genes especially involved in metamorphosis, sensory perception and immunity in the two stages. Among 22,622 unigenes, 169 unigenes were assigned to morphogenic pathways (i.e., Wnt, Hedgehog and hormone biosynthesis). For metamorphosis, 38 up-regulated genes in megalopae were associated with cytoskeleton construction, while, 52 up-regulated genes in juvenile were related to cuticle development and protein degradation. Several crucial genes involved in phototransduction and two olfactory-related genes were significantly up-regulated in megalopae. Moreover, 44 immunity-related genes were highly expressed in megalopae. This study provides a comprehensive view of brachyurization and benthic adaptation mechanisms in E. sinensis. (C) 2014 Elsevier B.V. All rights reserved.
关键词	Benthic Lifestyle Brachyurization Differential Gene Expression Eriocheir Sinensis Megalopae
DOI	10.1016/j.gene.2014.12.048
收录类别	SCI
语种	英语
WOS记录号	WOS:000349505100010
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/25347
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, EMBL, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Song, Chengwen,Cui, Zhaoxia,Hui, Min,et al. Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis[J]. GENE,2015,558(1):88-98.
APA	Song, Chengwen,Cui, Zhaoxia,Hui, Min,Liu, Yuan,Li, Yingdong,&Li, Xihong.(2015).Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis.GENE,558(1),88-98.
MLA	Song, Chengwen,et al."Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis".GENE 558.1(2015):88-98.

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