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Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue
Wang, Xueqin1,2; Xing, Ronge1; Chen, Zuoyuan3; Yu, Huahua1; Li, Rongfeng1; Li, Pengcheng1; Wang, XQ (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
2014-09-01
发表期刊FOOD & FUNCTION
卷号5期号:9页码:2113-2119
文章类型Article
摘要Mackerel protein hydrolysate (MPH) was purified through ultrafiltration membranes, and its effect and mechanism for anti-fatigue were investigated in mice. The result showed that MPH (<2.5 kDa) had effective free radical scavenging activities. Moreover, the MPH groups could significantly prolong exhaustion swimming time compared to the normal and other groups. The liver glycogen level was markedly increased by 33-35% and the BUN (16-17%), LA (14-19%) and MDA (16-31%) levels were decreased in the MPH group compared to that of the control group. In addition, MPH improved enzymatic antioxidant system by increasing the activities of SOD and GSH-Px. This study exhibited possible anti-fatigue mechanism of MPH, as follows: first, the MPH could supplement the concentration of blood glycogen and eliminate metabolites, which were related to fatigue; second, MPH with free radical scavenging ability could enhance the activities of antioxidant enzymes, which could alleviate fatigue.
学科领域Biochemistry & Molecular Biology ; Food Science & Technology
DOI10.1039/c4fo00121d
收录类别SCI
语种英语
WOS记录号WOS:000341016500013
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被引频次:44[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/24206
专题海洋生物技术研发中心
海洋环境工程技术研究发展中心
通讯作者Wang, XQ (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Univ Med Coll, Affiliated Hosp Qingdao, Dept Cardiol, Qingdao 266003, Peoples R China
第一作者单位中国科学院海洋研究所
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Wang, Xueqin,Xing, Ronge,Chen, Zuoyuan,et al. Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue[J]. FOOD & FUNCTION,2014,5(9):2113-2119.
APA Wang, Xueqin.,Xing, Ronge.,Chen, Zuoyuan.,Yu, Huahua.,Li, Rongfeng.,...&Wang, XQ .(2014).Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue.FOOD & FUNCTION,5(9),2113-2119.
MLA Wang, Xueqin,et al."Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue".FOOD & FUNCTION 5.9(2014):2113-2119.
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